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Professionally Delivered Local Antimicrobials in the Treatment of Patients with Periodontitis—A Narrative Review

Clinical Dentistry and Oral Radiology, College of Medicine and Dentistry, James Cook University, Smithfield, Cairns, QLD 4878, Australia
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Received: 8 December 2020 / Revised: 19 December 2020 / Accepted: 21 December 2020 / Published: 22 December 2020
(This article belongs to the Section Oral Hygiene, Periodontology and Peri-implant Diseases)
This review sheds light on the recent published scientific evidence relating to the use of professionally delivered local antimicrobial agents (LA’s). The review also analyses drug delivery systems available to date and provides an update on the latest scientific evidence about the benefits, limitations, and clinical results obtained by use of local drugs in the treatment of periodontal disease. The search strategy revealed randomized controlled trials (RCTs) that compared the efficacy of adjunctive LA’s to mechanical therapy alone. Based on the available evidence gathered from this review, we can infer that the use of local antimicrobial agents in conjunction to scaling and root debridement (SRD) delivers significant benefits in periodontal therapy and it is a useful aid, avoiding many of the side effects that systemic antibiotic therapy may involve. Local drug delivery (LDD) is an efficient and effective means of delivering drugs based on the evidence presented in the review. The authors of this review would suggest the use of local antimicrobials in cases of localized periodontitis or individual areas that do not respond to the usual mechanical therapy alone. This review summarizes the current use of local drug delivery in periodontal management ensuring that the general practitioners are able to choose an appropriate local antimicrobial. View Full-Text
Keywords: local antimicrobials; local antibiotics; topical oral antibiotic; local drug delivery; periodontitis; periodontal therapy; periodontal treatment; scaling and root planning; scaling and root debridement local antimicrobials; local antibiotics; topical oral antibiotic; local drug delivery; periodontitis; periodontal therapy; periodontal treatment; scaling and root planning; scaling and root debridement
MDPI and ACS Style

Sholapurkar, A.; Sharma, D.; Glass, B.; Miller, C.; Nimmo, A.; Jennings, E. Professionally Delivered Local Antimicrobials in the Treatment of Patients with Periodontitis—A Narrative Review. Dent. J. 2021, 9, 2. https://0-doi-org.brum.beds.ac.uk/10.3390/dj9010002

AMA Style

Sholapurkar A, Sharma D, Glass B, Miller C, Nimmo A, Jennings E. Professionally Delivered Local Antimicrobials in the Treatment of Patients with Periodontitis—A Narrative Review. Dentistry Journal. 2021; 9(1):2. https://0-doi-org.brum.beds.ac.uk/10.3390/dj9010002

Chicago/Turabian Style

Sholapurkar, Amar; Sharma, Dileep; Glass, Beverley; Miller, Catherine; Nimmo, Alan; Jennings, Ernest. 2021. "Professionally Delivered Local Antimicrobials in the Treatment of Patients with Periodontitis—A Narrative Review" Dent. J. 9, no. 1: 2. https://0-doi-org.brum.beds.ac.uk/10.3390/dj9010002

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