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Review

The Impact of Oral Health on Respiratory Viral Infection

1
Department of Health Science, Hyogo University, Kakogawa 675-0195, Japan
2
Department of Bacteriology, National Institute of Infectious Diseases, Tokyo 162-8640, Japan
*
Author to whom correspondence should be addressed.
Academic Editor: Guglielmo Campus
Received: 5 March 2021 / Revised: 6 April 2021 / Accepted: 9 April 2021 / Published: 13 April 2021
(This article belongs to the Section Oral Hygiene, Periodontology and Peri-implant Diseases)
Influenza virus and severe acute respiratory syndrome coronavirus (SARS-CoV-2) have caused respiratory diseases worldwide. Coronavirus disease 2019 (COVID-19) is now a global health concern requiring emergent measures. These viruses enter the human body through the oral cavity and infect respiratory cells. Since the oral cavity has a complex microbiota, influence of oral bacteria on respiratory virus infection is considered. Saliva has immune molecules which work as the front line in the biophylactic mechanism and has considerable influence on the incidence and progression of respiratory viral infection. Salivary scavenger molecules, such as gp340 and sialic acid, have been reported to exert anti-influenza virus activity. Salivary secretory immunoglobulin A (SIgA) has potential to acquire immunity against these viruses. Biological features of the oral cavity are thought to affect viral infection in respiratory organs in various ways. In this review, we reviewed the literature addressing the impact of oral conditions on respiratory infectious diseases caused by viruses. View Full-Text
Keywords: SARS-CoV-2; influenza virus; oral cavity; saliva SARS-CoV-2; influenza virus; oral cavity; saliva
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MDPI and ACS Style

Tada, A.; Senpuku, H. The Impact of Oral Health on Respiratory Viral Infection. Dent. J. 2021, 9, 43. https://0-doi-org.brum.beds.ac.uk/10.3390/dj9040043

AMA Style

Tada A, Senpuku H. The Impact of Oral Health on Respiratory Viral Infection. Dentistry Journal. 2021; 9(4):43. https://0-doi-org.brum.beds.ac.uk/10.3390/dj9040043

Chicago/Turabian Style

Tada, Akio, and Hidenobu Senpuku. 2021. "The Impact of Oral Health on Respiratory Viral Infection" Dentistry Journal 9, no. 4: 43. https://0-doi-org.brum.beds.ac.uk/10.3390/dj9040043

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