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Review

Genus Stachys: A Review of Traditional Uses, Phytochemistry and Bioactivity

Department of Pharmacognosy and Chemistry of Natural Products, Faculty of Pharmacy, School of Health Sciences, National & Kapodistrian University of Athens, Panepistimiopolis, Zografou, 15771 Athens, Greece
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Received: 11 August 2020 / Revised: 18 September 2020 / Accepted: 25 September 2020 / Published: 29 September 2020
Background: The genus Stachys L. (Lamiaceae) includes about 300 species as annual or perennial herbs or small shrubs, spread in temperate regions of Mediterranean, Asia, America and southern Africa. Several species of this genus are extensively used in various traditional medicines. They are consumed as herbal preparations for the treatment of stress, skin inflammations, gastrointestinal disorders, asthma and genital tumors. Previous studies have investigated the chemical constituents and the biological activities of these species. Thus, the present review compiles literature data on ethnomedicine, phytochemistry, pharmacological activities, clinical studies and the toxicity of genus Stachys. Methods: Comprehensive research of previously published literature was performed for studies on the traditional uses, bioactive compounds and pharmacological properties of the genus Stachys, using databases with different key search words. Results: This survey documented 60 Stachys species and 10 subspecies for their phytochemical profiles, including 254 chemical compounds and reported 19 species and 4 subspecies for their pharmacological properties. Furthermore, 25 species and 6 subspecies were found for their traditional uses. Conclusions: The present review highlights that Stachys spp. consist an important source of bioactive phytochemicals and exemplifies the uncharted territory of this genus for new research studies. View Full-Text
Keywords: Stachys L.; traditional uses; pharmacological activities; phytochemicals; bioactive compounds Stachys L.; traditional uses; pharmacological activities; phytochemicals; bioactive compounds
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MDPI and ACS Style

Tomou, E.-M.; Barda, C.; Skaltsa, H. Genus Stachys: A Review of Traditional Uses, Phytochemistry and Bioactivity. Medicines 2020, 7, 63. https://0-doi-org.brum.beds.ac.uk/10.3390/medicines7100063

AMA Style

Tomou E-M, Barda C, Skaltsa H. Genus Stachys: A Review of Traditional Uses, Phytochemistry and Bioactivity. Medicines. 2020; 7(10):63. https://0-doi-org.brum.beds.ac.uk/10.3390/medicines7100063

Chicago/Turabian Style

Tomou, Ekaterina-Michaela, Christina Barda, and Helen Skaltsa. 2020. "Genus Stachys: A Review of Traditional Uses, Phytochemistry and Bioactivity" Medicines 7, no. 10: 63. https://0-doi-org.brum.beds.ac.uk/10.3390/medicines7100063

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