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Autoimmune Disorders & COVID-19
Opinion

COVID-19 Infection and Neuropathological Features

1
Instituto de Biofisica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-170, Brazil
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Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-170, Brazil
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Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro 21040-360, Brazil
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Departamento de Química Orgânica, Instituto de Química, Universidade Federal Rural do Rio de Janeiro, Rio de Janeiro 23890-000, Brazil
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Departamento de Microbiologia e Imunologia Veterinária, Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro, Rio de Janeiro 23890-000, Brazil
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Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21044-020, Brazil
*
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Academic Editor: Akram Zaaqoq
Received: 25 August 2021 / Revised: 2 October 2021 / Accepted: 6 October 2021 / Published: 11 October 2021
The pathology associated with COVID-19 infection is progressively being revealed. Recent postmortem assessments have revealed acute airway inflammation as well as diffuse alveolar damage, which bears resemblance to severe acute respiratory syndromes induced by both SARS-CoV and MERS-CoV infections. Although recent papers have highlighted some neuropathologies associated with COVID-19 infection, little is known about this topic of great importance in the area of public health. Here, we discuss how neuroinflammation related to COVID-19 could be triggered by direct viral neuroinvasion and/or cytokine release over the course of the infection. View Full-Text
Keywords: COVID-19 infection; neuropathology; autoantibodies; neuroinflammation COVID-19 infection; neuropathology; autoantibodies; neuroinflammation
MDPI and ACS Style

Freire-de-Lima, L.; Scovino, A.M.; Marques da Fonseca, L.; Barreto Menezes, C.C.; Santos, C.A.d.N.; Freire de Lima, M.E.; Decote-Ricardo, D.; Freire-de-Lima, M.; da Costa, K.M.; dos Reis, J.S.; Rodrigues da Costa Santos, M.A.; Freire-de-Lima, C.G.; Morrot, A. COVID-19 Infection and Neuropathological Features. Medicines 2021, 8, 59. https://0-doi-org.brum.beds.ac.uk/10.3390/medicines8100059

AMA Style

Freire-de-Lima L, Scovino AM, Marques da Fonseca L, Barreto Menezes CC, Santos CAdN, Freire de Lima ME, Decote-Ricardo D, Freire-de-Lima M, da Costa KM, dos Reis JS, Rodrigues da Costa Santos MA, Freire-de-Lima CG, Morrot A. COVID-19 Infection and Neuropathological Features. Medicines. 2021; 8(10):59. https://0-doi-org.brum.beds.ac.uk/10.3390/medicines8100059

Chicago/Turabian Style

Freire-de-Lima, Leonardo, Aline M. Scovino, Leonardo Marques da Fonseca, Camilla C. Barreto Menezes, Carlos A.d.N. Santos, Marco E. Freire de Lima, Debora Decote-Ricardo, Matheus Freire-de-Lima, Kelli M. da Costa, Jhenifer S. dos Reis, Marcos A. Rodrigues da Costa Santos, Celio G. Freire-de-Lima, and Alexandre Morrot. 2021. "COVID-19 Infection and Neuropathological Features" Medicines 8, no. 10: 59. https://0-doi-org.brum.beds.ac.uk/10.3390/medicines8100059

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