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Data Descriptor

Data on the Quantification of Aspartate, GABA and Glutamine Levels in the Spinal Cord of Larval Sea Lampreys after a Complete Spinal Cord Injury

1
Department of Functional Biology, CIBUS, Faculty of Biology, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain
2
Ministry of Health, Paseo del Prado, 18, 28014 Madrid, Spain
3
Laboratory of Toxicology, Sciences School, University of Vigo, Las Lagunas s/n, 32004 Ourense, Spain
*
Author to whom correspondence should be addressed.
Deceased.
Academic Editor: Juraj Gregáň
Received: 4 May 2021 / Revised: 21 May 2021 / Accepted: 23 May 2021 / Published: 24 May 2021
We used high-performance liquid chromatography (HPLC) methods to quantify aspartate, GABA, and glutamine levels in the spinal cord of larval sea lampreys following a complete spinal cord injury. Mature larval sea lampreys recover spontaneously from a complete spinal cord transection and the changes in neurotransmitter systems after spinal cord injury might be related to their amazing regenerative capabilities. The data presented here show the concentration of the aminoacidergic neurotransmitters GABA (and its precursor glutamine) and aspartate in the spinal cord of control (non-injured) and 2-, 4-, and 10-week post-lesion animals. Statistical analyses showed that GABA and aspartate levels significantly increase in the spinal cord four weeks after a complete spinal cord injury and that glutamine levels decrease 10 weeks after injury as compared to controls. These data might be of interest to those studying the role of neurotransmitters and neuromodulators in recovery from spinal cord injury in vertebrates. View Full-Text
Keywords: aspartate; GABA; glutamine; HPLC; spinal cord injury; lampreys aspartate; GABA; glutamine; HPLC; spinal cord injury; lampreys
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    Doi: http://0-doi.org.brum.beds.ac.uk/10.5281/zenodo.4772417
    Description: Aspartate, GABA and glutamine concentration (ng/mg protein) in each HPLC sample (7 spinal cord pieces/sample). The dataset can also be found at http://0-doi.org.brum.beds.ac.uk/10.5281/zenodo.4772417.
MDPI and ACS Style

Fernández-López, B.; Pereiro, N.; Lafuente, A.; Rodicio, M.C.; Barreiro-Iglesias, A. Data on the Quantification of Aspartate, GABA and Glutamine Levels in the Spinal Cord of Larval Sea Lampreys after a Complete Spinal Cord Injury. Data 2021, 6, 54. https://0-doi-org.brum.beds.ac.uk/10.3390/data6060054

AMA Style

Fernández-López B, Pereiro N, Lafuente A, Rodicio MC, Barreiro-Iglesias A. Data on the Quantification of Aspartate, GABA and Glutamine Levels in the Spinal Cord of Larval Sea Lampreys after a Complete Spinal Cord Injury. Data. 2021; 6(6):54. https://0-doi-org.brum.beds.ac.uk/10.3390/data6060054

Chicago/Turabian Style

Fernández-López, Blanca, Natividad Pereiro, Anunciación Lafuente, María C. Rodicio, and Antón Barreiro-Iglesias. 2021. "Data on the Quantification of Aspartate, GABA and Glutamine Levels in the Spinal Cord of Larval Sea Lampreys after a Complete Spinal Cord Injury" Data 6, no. 6: 54. https://0-doi-org.brum.beds.ac.uk/10.3390/data6060054

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