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Review

Carbon Nanohorns as Effective Nanotherapeutics in Cancer Therapy

1
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy
2
Children’s Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Randwick, NSW 2031, Australia
3
School of Women’s and Children’s Health, Faculty of Medicine, UNSW Sydney, NSW 2052, Australia
4
ARC Centre of Excellence for Convergent BioNano Science and Technology, Australian Centre for NanoMedicine, UNSW Sydney, NSW 2052, Australia
5
Leibniz Institute of Solid State and Material Research Dresden, 01069 Dresden, Germany
*
Authors to whom correspondence should be addressed.
Received: 4 December 2020 / Revised: 22 December 2020 / Accepted: 23 December 2020 / Published: 27 December 2020
(This article belongs to the Special Issue Functional Carbons and Carbides: Bioapplications and Beyond)
Different carbon nanostructures have been explored as functional materials for the development of effective nanomaterials in cancer treatment applications. This review mainly aims to discuss the features, either strength or weakness, of carbon nanohorn (CNH), carbon conical horn-shaped nanostructures of sp2 carbon atoms. The interest for these materials arises from their ability to couple the clinically relevant properties of carbon nanomaterials as drug carriers with the negligible toxicity described in vivo. Here, we offer a comprehensive overview of the recent advances in the use of CNH in cancer treatments, underlining the benefits of each functionalization route and approach, as well as the biological performances of either loaded and unloaded materials, while discussing the importance of delivery devices. View Full-Text
Keywords: carbon nanohorns; cancer treatment; drug delivery; functional materials; nanohybrids carbon nanohorns; cancer treatment; drug delivery; functional materials; nanohybrids
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MDPI and ACS Style

Curcio, M.; Cirillo, G.; Saletta, F.; Michniewicz, F.; Nicoletta, F.P.; Vittorio, O.; Hampel, S.; Iemma, F. Carbon Nanohorns as Effective Nanotherapeutics in Cancer Therapy. C 2021, 7, 3. https://0-doi-org.brum.beds.ac.uk/10.3390/c7010003

AMA Style

Curcio M, Cirillo G, Saletta F, Michniewicz F, Nicoletta FP, Vittorio O, Hampel S, Iemma F. Carbon Nanohorns as Effective Nanotherapeutics in Cancer Therapy. C. 2021; 7(1):3. https://0-doi-org.brum.beds.ac.uk/10.3390/c7010003

Chicago/Turabian Style

Curcio, Manuela, Giuseppe Cirillo, Federica Saletta, Filip Michniewicz, Fiore P. Nicoletta, Orazio Vittorio, Silke Hampel, and Francesca Iemma. 2021. "Carbon Nanohorns as Effective Nanotherapeutics in Cancer Therapy" C 7, no. 1: 3. https://0-doi-org.brum.beds.ac.uk/10.3390/c7010003

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