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Brief Report

Utility of Direct Fast Scarlet Staining in the Histopathological Diagnosis of Eosinophilic Esophagitis: A Short Report

1
Department of Diagnostic Pathology & Research Center of Diagnostic Pathology, Gifu Municipal Hospital, 7-1 Kashima-cho, Gifu City 500-8513, Japan
2
Department of Internal Medicine, Gifu Municipal Hospital, Gifu City 500-8513, Japan
*
Author to whom correspondence should be addressed.
Gastrointest. Disord. 2020, 2(4), 448-455; https://0-doi-org.brum.beds.ac.uk/10.3390/gidisord2040040
Received: 7 October 2020 / Revised: 29 October 2020 / Accepted: 29 October 2020 / Published: 9 November 2020
Eosinophilic esophagitis (EoE), an atopic disease of the esophagus, has become increasingly recognized over the last 15 years. The epidemiology of EoE has now been reported from many countries around the world. While the clinical diagnosis of this disease depends on the patient’s clinical manifestations, the final diagnosis should be made based on the histopathological examination of esophageal mucosal biopsies. In the diagnosis of EoE, to facilitate the appropriate treatment of patients, it is extremely important to precisely recognize the presence of eosinophils in biopsy specimens of the esophageal mucosa. If eosinophils are present, EoE patients should be referred to an allergist for appropriate management with dietary modification, pharmacological agents (including corticosteroids), and/or mechanical dilation of the esophagus. We herein present and recommend the use of direct fast scarlet staining for the easy and precise recognition of eosinophils in biopsy specimens of the esophageal mucosa, a technique that has been routinely used in our laboratory. View Full-Text
Keywords: eosinophilic esophagitis; eosinophils; esophageal mucosal biopsy; direct fast scarlet staining eosinophilic esophagitis; eosinophils; esophageal mucosal biopsy; direct fast scarlet staining
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MDPI and ACS Style

Tanaka, T.; Watanabe, N.; Kato, T.; Aoki, R.; Ogiso, T.; Sugiyama, A.; Tomita, E. Utility of Direct Fast Scarlet Staining in the Histopathological Diagnosis of Eosinophilic Esophagitis: A Short Report. Gastrointest. Disord. 2020, 2, 448-455. https://0-doi-org.brum.beds.ac.uk/10.3390/gidisord2040040

AMA Style

Tanaka T, Watanabe N, Kato T, Aoki R, Ogiso T, Sugiyama A, Tomita E. Utility of Direct Fast Scarlet Staining in the Histopathological Diagnosis of Eosinophilic Esophagitis: A Short Report. Gastrointestinal Disorders. 2020; 2(4):448-455. https://0-doi-org.brum.beds.ac.uk/10.3390/gidisord2040040

Chicago/Turabian Style

Tanaka, Takuji, Naoki Watanabe, Tomohiro Kato, Ryogo Aoki, Tomio Ogiso, Akihiko Sugiyama, and Eiichi Tomita. 2020. "Utility of Direct Fast Scarlet Staining in the Histopathological Diagnosis of Eosinophilic Esophagitis: A Short Report" Gastrointestinal Disorders 2, no. 4: 448-455. https://0-doi-org.brum.beds.ac.uk/10.3390/gidisord2040040

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