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Polymeric Bioinks for 3D Hepatic Printing

Institute of Chemical Technology, Mumbai, Marathwada Campus Jalna, BT-6/7, Biotechnology Park, Additional MIDC Area, Aurangabad Road, Jalna 431203, Maharashtra, India
Department of Technology, Savitribai Phule Pune University, Ganeshkhind, Pune 411007, Maharashtra, India
Authors to whom correspondence should be addressed.
Received: 4 December 2020 / Revised: 26 January 2021 / Accepted: 26 January 2021 / Published: 1 February 2021
(This article belongs to the Section Organic Materials and Polymers)
Three-dimensional (3D) printing techniques have revolutionized the field of tissue engineering. This is especially favorable to construct intricate tissues such as liver, as 3D printing allows for the precise delivery of biomaterials, cells and bioactive molecules in complex geometries. Bioinks made of polymers, of both natural and synthetic origin, have been very beneficial to printing soft tissues such as liver. Using polymeric bioinks, 3D hepatic structures are printed with or without cells and biomolecules, and have been used for different tissue engineering applications. In this review, with the introduction to basic 3D printing techniques, we discuss different natural and synthetic polymers including decellularized matrices that have been employed for the 3D bioprinting of hepatic structures. Finally, we focus on recent advances in polymeric bioinks for 3D hepatic printing and their applications. The studies indicate that much work has been devoted to improvising the design, stability and longevity of the printed structures. Others focus on the printing of tissue engineered hepatic structures for applications in drug screening, regenerative medicine and disease models. More attention must now be diverted to developing personalized structures and stem cell differentiation to hepatic lineage. View Full-Text
Keywords: 3D bioprinting; polymeric bioinks; hepatic tissue engineering 3D bioprinting; polymeric bioinks; hepatic tissue engineering
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MDPI and ACS Style

Sarkar, J.; Kamble, S.C.; Kashikar, N.C. Polymeric Bioinks for 3D Hepatic Printing. Chemistry 2021, 3, 164-181.

AMA Style

Sarkar J, Kamble SC, Kashikar NC. Polymeric Bioinks for 3D Hepatic Printing. Chemistry. 2021; 3(1):164-181.

Chicago/Turabian Style

Sarkar, Joyita, Swapnil C. Kamble, and Nilambari C. Kashikar 2021. "Polymeric Bioinks for 3D Hepatic Printing" Chemistry 3, no. 1: 164-181.

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