Fluid-Structure Interaction Analysis of Subject-Specific Mitral Valve Regurgitation Treatment with an Intra-Valvular Spacer
Abstract
:1. Introduction
2. Materials and Methods
2.1. Model Development
2.2. Fiber Orientation
2.3. Constitutive Model
2.4. Numerical Methods
2.5. Application to Assessment of Spacer Efficacy
3. Results
4. Discussion
5. Limitations and Future Work
6. Conclusions
Author Contributions
Funding
Conflicts of Interest
Abbreviations
MR | Mitral Regurgitation |
DMR | Degenerative Mitral Regurgitation |
FMR | Functional Mitral Regurgitation |
FDA | Food and Drug Administration |
MV | Mitral Valve |
FSI | Fluid-Structure Interaction |
ROA | Regurgitant Orifice Area |
CT | Micro-Computed Tomography |
SPH | Smoothed Particle Hydrodynamics |
GPU | Graphics Processing Unit |
3D | Three-Dimensional |
1D | One-Dimensional |
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Toma, M.; Einstein, D.R.; Bloodworth, C.H., IV; Kohli, K.; Cochran, R.P.; Kunzelman, K.S.; Yoganathan, A.P. Fluid-Structure Interaction Analysis of Subject-Specific Mitral Valve Regurgitation Treatment with an Intra-Valvular Spacer. Prosthesis 2020, 2, 65-75. https://0-doi-org.brum.beds.ac.uk/10.3390/prosthesis2020007
Toma M, Einstein DR, Bloodworth CH IV, Kohli K, Cochran RP, Kunzelman KS, Yoganathan AP. Fluid-Structure Interaction Analysis of Subject-Specific Mitral Valve Regurgitation Treatment with an Intra-Valvular Spacer. Prosthesis. 2020; 2(2):65-75. https://0-doi-org.brum.beds.ac.uk/10.3390/prosthesis2020007
Chicago/Turabian StyleToma, Milan, Daniel R. Einstein, Charles H. Bloodworth, IV, Keshav Kohli, Richard P. Cochran, Karyn S. Kunzelman, and Ajit P. Yoganathan. 2020. "Fluid-Structure Interaction Analysis of Subject-Specific Mitral Valve Regurgitation Treatment with an Intra-Valvular Spacer" Prosthesis 2, no. 2: 65-75. https://0-doi-org.brum.beds.ac.uk/10.3390/prosthesis2020007