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Percutaneous Mitral Valve Repair with the MitraClip System in the Current Clinical Practice

Cardiology, Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum, University of Bologna, 40138 Bologna, Italy
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Received: 17 November 2020 / Revised: 12 January 2021 / Accepted: 18 January 2021 / Published: 22 January 2021
Severe mitral valve regurgitation (MR) carries a significant burden both in prognosis and quality of life of patients, as well as on healthcare systems, with high rates of hospitalization for heart failure. While mitral valve surgery constitutes the first-line treatment option for primary MR in suitable patients, surgical treatment for secondary severe MR remains controversial, with a substantial lack of evidence on a survival benefit. In recent decades, percutaneous mitral valve repair has emerged as an alternative treatment for patients deemed not suitable for surgery. Among several devices under development or evaluation, the MitraClip system is the most widespread and is supported by the strongest evidence. While the role of MitraClip in patients with chronic primary MR who are not deemed suitable for surgery is well established, with consistent data showing improvement in both prognosis and quality of life, MitraClip treatment in secondary MR is a rapidly evolving field. Two recent randomized clinical trials generated apparently controversial results but actually provided an interesting pathophysiologic frame that could help discerning patients who will benefit from the procedure versus patients who will not. In this review, we will discuss current treatment options for mitral regurgitation, focusing on percutaneous mitral valve repair with the MitraClip system. View Full-Text
Keywords: mitral regurgitation; transcatheter mitral valve repair; TMVR; MitraClip; heart failure mitral regurgitation; transcatheter mitral valve repair; TMVR; MitraClip; heart failure
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MDPI and ACS Style

Sorrentino, S.; Berardini, A.; Statuto, G.; Angeletti, A.; Massaro, G.; Capobianco, C.; Piemontese, G.P.; Spadotto, A.; Toniolo, S.; Caponetti, A.G.; Ditaranto, R.; Parisi, V.; Minnucci, M.; Ferrara, V.; Galiè, N.; Biagini, E. Percutaneous Mitral Valve Repair with the MitraClip System in the Current Clinical Practice. Hearts 2021, 2, 74-86. https://0-doi-org.brum.beds.ac.uk/10.3390/hearts2010007

AMA Style

Sorrentino S, Berardini A, Statuto G, Angeletti A, Massaro G, Capobianco C, Piemontese GP, Spadotto A, Toniolo S, Caponetti AG, Ditaranto R, Parisi V, Minnucci M, Ferrara V, Galiè N, Biagini E. Percutaneous Mitral Valve Repair with the MitraClip System in the Current Clinical Practice. Hearts. 2021; 2(1):74-86. https://0-doi-org.brum.beds.ac.uk/10.3390/hearts2010007

Chicago/Turabian Style

Sorrentino, Sergio; Berardini, Alessandra; Statuto, Giovanni; Angeletti, Andrea; Massaro, Giulia; Capobianco, Claudio; Piemontese, Giuseppe P.; Spadotto, Alberto; Toniolo, Sebastiano; Caponetti, Angelo G.; Ditaranto, Raffaello; Parisi, Vanda; Minnucci, Matteo; Ferrara, Valentina; Galiè, Nazzareno; Biagini, Elena. 2021. "Percutaneous Mitral Valve Repair with the MitraClip System in the Current Clinical Practice" Hearts 2, no. 1: 74-86. https://0-doi-org.brum.beds.ac.uk/10.3390/hearts2010007

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