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The Effects of Endometriosis on Ovarian Functions

Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8523, Japan
Author to whom correspondence should be addressed.
Academic Editors: Osamu Hiraike and Akira Iwase
Received: 28 April 2021 / Revised: 27 May 2021 / Accepted: 31 May 2021 / Published: 3 June 2021
(This article belongs to the Special Issue Impact of Endometriosis on Women’s Health)
Infertility is a main manifestation of endometriosis, though the exact pathogenesis of endometriosis-associated infertility remains unclear. Compromised ovarian functions may be one of the causes of endometriosis related infertility. The ovarian function can be classified into three basic elements, (1) production of ovarian hormones, (2) maintenance of follicular development until ovulation, and (3) reservoir of dormant oocytes (ovarian reserve). The effects of endometriosis on ovarian hormone production and follicular development are inconclusive. Ovarian endometrioma is common phonotype of endometriosis. Development of endometrioma per se may affect ovarian reserve. Surgery for endometriomas further diminish ovarian reserve, especially women with bilateral involvement. Early intervention with surgery and/or medical treatment may be beneficial, though firm evidence is lacking. When surgery is chosen in women at reproductive age, specific techniques that spare ovarian function should be considered. View Full-Text
Keywords: endometriosis; endometrioma; ovarian hormones; oocyte; ovarian reserve endometriosis; endometrioma; ovarian hormones; oocyte; ovarian reserve
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MDPI and ACS Style

Kitajima, M.; Matsumoto, K.; Kajimura, I.; Harada, A.; Miyashita, N.; Matsumura, A.; Kitajima, Y.; Miura, K. The Effects of Endometriosis on Ovarian Functions. Endocrines 2021, 2, 142-149.

AMA Style

Kitajima M, Matsumoto K, Kajimura I, Harada A, Miyashita N, Matsumura A, Kitajima Y, Miura K. The Effects of Endometriosis on Ovarian Functions. Endocrines. 2021; 2(2):142-149.

Chicago/Turabian Style

Kitajima, Michio, Kanako Matsumoto, Itsuki Kajimura, Ayumi Harada, Noriko Miyashita, Asako Matsumura, Yuriko Kitajima, and Kiyonori Miura. 2021. "The Effects of Endometriosis on Ovarian Functions" Endocrines 2, no. 2: 142-149.

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