- Structure and dynamics of biomolecules and their assemblies: proteins, nucleic acids, biological membranes and supramolecular assemblies;
- Biomolecular Machines: enzymes, motors, channels, receptors, transporters, circadian clocks, and other biological nanomachines;
- Genetics and Gene Expression mechanisms: genome architecture, chromatin structure and dynamics, gene expression, DNA repair, genome editing, epigenetics;
- Cell Biophysics: electrophysiology, cell division, signaling and migration, cell differentiation, tissue organization and tissue engineering;
- Biophysical Techniques and Instrumentation: methods for the high-resolution structural and dynamic analysis of biomolecular systems, single-molecule spectroscopy and manipulation, biological imaging methods and applications, biosensor engineering and design;
- Theory and Modeling of Biological Systems: applications of statistical mechanical modeling, computer simulations, or methods for the quantitative analysis of large biological datasets aiming at the rationalization or prediction of experimentally measured phenomena.
- Biomechanics, Sensing and Signaling;
- Quantitative Synthetic Biology;
- Bioengineering, Nanotechnology and Biomaterials.
Conflicts of Interest
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Short Biography of Authors
Prof. Matthias Buck, M.A., D.Phil. is Professor in the Departments of Physiology and Bio-physics, Neuroscience and Pharmacology at Case Western Reserve University School of Medicine. He is a native of Hamburg, and prior to starting his independent career in Cleveland in 2002, he did his undergraduate studies at the University of Cambridge, and obtained his doctorate from Oxford University, followed by postdoctoral work at Har-vard University and the Memorial Sloan Kettering Cancer Center. He is the Director of the North East Ohio High Field Nuclear Magnetic Resonance Facility. His research inter-est focuses on the characterization of protein-protein and protein-membrane interactions at the molecular level, using structural biology and biophysical tools as well as computa-tional modeling and simulations. His team is currently working on the regulatory mech-anisms of Plexin and Eph transmembrane receptors as well as on small membrane bound Ras and Rho GTPases. He enjoys traveling and when he is not working is playing with his two young daughters, likes EDM, Wine, Photography and Poetry (Google Scholar h-index = 33).
Prof. Victor Muñoz is a Professor of Bioengineering at the University of California Merced and Director of the NSF-CREST Center for Cellular and Biomolecular Machines. He was born in Liège (Belgium) and raised in Madrid (Spain). He carried out his PhD at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and his postdoctoral training at the US National Institutes of Health in Bethesda, Maryland. During his independent career he has been as at the University of Maryland as Assistant and Associate Professor (2000–2007), at the Spanish National Research Council as Re-search Professor (2007–2014), and at UC Merced since 2014. He is a Packard Fellow (2001), Searle Scholar (2002) and EMBO member (2009). His research area is experi-mental and computational protein biophysics and biomolecular engineering. Current re-search interests are in protein folding, binding and function, eukaryotic gene expression, calcium signaling and intrinsically disordered proteins, as well as cool technology-based projects in advanced protein biosensors, allosteric macromolecular assemblies, and mo-lecular diagnostics. In his leisure time he enjoys hiking with his two huskies, riding his Ducati and sky diving (Google Scholar h-index = 49).
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