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Proceedings

Cumulative Cytotoxicity Assay of the Aqueous and Ethanolic Extracts of the Selected Medicinal Plants Using Crown Gall Tumor Disc Bioassay

1
Konkan Gyanpeeth Rahul Dharkar College of Pharmacy and Research Institute, Karjat, Raigad 410201, India
2
Hon’ble Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur, Jalgaon 425503, India
*
Author to whom correspondence should be addressed.
Presented at the 24th International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2020; Available online: https://ecsoc-24.sciforum.net/.
Published: 14 November 2020
The present study was carried out to test an in vivo crown gall tumor disc bioassay using potato discs of the aqueous and ethanolic extracts of Annona reticulata with Allium sativum, Allium fistolisum, Brassica oleraceae, and then correlate the cytotoxicity results with the known pharmacological activities of the plants. Cytotoxicity was evaluated according to the crown gall tumor disc bioassay, a highly specific, quantitative method that requires only a short period of time to return results of crown gall tumor formation. The results shows the cumulative activity of the extracts of Annona reticulate extract with Allium sativum, Allium fistolisum and Brassica oleraceae extracts and shown they were potent against the bioassay as compared to their being used alone with combined extracts. The results indicated that their bioactive components have considerable pharmacological effects. Thus, the results supported the uses of these plant species in traditional medicine.
Keywords: crown gall tumor disc bioassay; Annona reticulate; Allium sativum; Allium fistolisum and Brassica oleraceae; potato disc bioassay; antitumour; cytotoxicity crown gall tumor disc bioassay; Annona reticulate; Allium sativum; Allium fistolisum and Brassica oleraceae; potato disc bioassay; antitumour; cytotoxicity
MDPI and ACS Style

Waghulde, S.; Gorde, N.; Baviskar, T.; Patil, P.; Singh, S.; Kale, M.K.; Patil, V.R. Cumulative Cytotoxicity Assay of the Aqueous and Ethanolic Extracts of the Selected Medicinal Plants Using Crown Gall Tumor Disc Bioassay. Chem. Proc. 2021, 3, 136. https://0-doi-org.brum.beds.ac.uk/10.3390/ecsoc-24-08297

AMA Style

Waghulde S, Gorde N, Baviskar T, Patil P, Singh S, Kale MK, Patil VR. Cumulative Cytotoxicity Assay of the Aqueous and Ethanolic Extracts of the Selected Medicinal Plants Using Crown Gall Tumor Disc Bioassay. Chemistry Proceedings. 2021; 3(1):136. https://0-doi-org.brum.beds.ac.uk/10.3390/ecsoc-24-08297

Chicago/Turabian Style

Waghulde, Sandeep, Nilesh Gorde, Tushar Baviskar, Praful Patil, Shweta Singh, Mohan K. Kale, and Vijay R. Patil 2021. "Cumulative Cytotoxicity Assay of the Aqueous and Ethanolic Extracts of the Selected Medicinal Plants Using Crown Gall Tumor Disc Bioassay" Chemistry Proceedings 3, no. 1: 136. https://0-doi-org.brum.beds.ac.uk/10.3390/ecsoc-24-08297

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