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Proceeding Paper

Synthesis and Insecticidal Activity of O-alkylated Oxirane Eugenol Derivatives

1
Centre of Chemistry (CQ-UM), University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal
2
REQUIMTE/LAQV, Laboratory of Pharmacognosy, Department of Chemistry, Faculty of Pharmacy, University of Porto, R. Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal
3
Centre of Physics (CFUM), University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal
*
Author to whom correspondence should be addressed.
Presented at the 24th International Electronic Conference on Synthetic Organic Chemistry, 15 November–15 December 2020; Available online: https://ecsoc-24.sciforum.net/.
Academic Editors: Julio A. Seijas and M. Pilar Vázquez-Tato
Published: 14 November 2020
The synthesis of three O-alkylated eugenol derivatives, bearing a hydroxypropyl chain and propyl esters, were synthesized and further converted into the corresponding oxiranes. Oxirane derivatives were then evaluated against their effect upon the viability of the insect cell line Sf9 (Spodoptera frugiperda), in comparison with the starting O-alkylates. The results pointing to their potential as bioinsecticides, with structural changes eliciting significant effects in terms of potency.
Keywords: essential oils; eugenol derivatives; eugenol epoxide; bioinsecticides; natural products essential oils; eugenol derivatives; eugenol epoxide; bioinsecticides; natural products
MDPI and ACS Style

Fernandes, M.J.G.; Pereira, D.M.; Pereira, R.B.; Fortes, A.G.; Castanheira, E.M.S.; Gonçalves, M.S.T. Synthesis and Insecticidal Activity of O-alkylated Oxirane Eugenol Derivatives. Chem. Proc. 2021, 3, 36. https://0-doi-org.brum.beds.ac.uk/10.3390/ecsoc-24-08335

AMA Style

Fernandes MJG, Pereira DM, Pereira RB, Fortes AG, Castanheira EMS, Gonçalves MST. Synthesis and Insecticidal Activity of O-alkylated Oxirane Eugenol Derivatives. Chemistry Proceedings. 2021; 3(1):36. https://0-doi-org.brum.beds.ac.uk/10.3390/ecsoc-24-08335

Chicago/Turabian Style

Fernandes, Maria José G., David M. Pereira, Renato B. Pereira, A. Gil Fortes, Elisabete M. S. Castanheira, and M. Sameiro T. Gonçalves 2021. "Synthesis and Insecticidal Activity of O-alkylated Oxirane Eugenol Derivatives" Chemistry Proceedings 3, no. 1: 36. https://0-doi-org.brum.beds.ac.uk/10.3390/ecsoc-24-08335

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