Twitter is a major tool for communication during emergencies and disasters. This study aimed to investigate Twitter use during natural hazards and pandemics. The included studies reported the role of Twitter in disasters triggered by natural hazards. Electronic databases were used for a comprehensive literature search to identify the records that match the mentioned inclusion criteria published through May 2020. Forty-five articles met the selection criteria and were included in the review. These indicated ten functions of Twitter in disasters, including early warning, dissemination of information, advocacy, assessment, risk communication, public sentiment, geographical analysis, charity, collaboration with influencers and building trust. Preventing the spread of misinformation is one of the most important issues in times of disaster, especially pandemics. Sharing accurate, transparent and prompt information from emergency organizations and governments can help. Moreover, analyzing Twitter data can be a good way to understand the mental state of the community, estimate the number of injured people, estimate the points affected by disasters and model the prevalence of epidemics. Therefore, various groups such as politicians, government, nongovernmental organizations, aid workers and the health system can use this information to plan and implement interventions.