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Review

Pain Sensitivity in Schizophrenia Spectrum Disorders: A Narrative Review of Recent Work

1
Department of Mental Health, Institut d’Investigació i Innovació Parc Taulí (I3PT), Parc Taulí University Hospital, Autonomous University of Barcelona (UAB), 08280 Barcelona, Spain
2
Department of Mental Health, Consorci Sanitari del Maresme, CIBERSAM, 08304 Mataró, Spain
3
Department of Psychiatry, University of Toronto, Toronto, ON M5P 3L6, Canada
*
Author to whom correspondence should be addressed.
Received: 17 January 2021 / Revised: 4 February 2021 / Accepted: 8 February 2021 / Published: 11 February 2021
Many patients with schizophrenia seem relatively immune to physical pain while others complain of constant pain. This may result from disturbances or alterations of the sensory threshold for pain in populations with psychosis, a possibility for which there is some preliminary evidence. The inconsistency in pain perception may, in part, be explained by the treatments patients receive, but treatment-naïve patients also exhibit differences in response to pain. This suggests that decreased pain sensitivity may represent a specific psychosis endophenotype. Thus far, few experimental studies have investigated sensory thresholds, pain modalities, or other factors contributing to the perception or expression of physical pain in psychosis. A digital search for information on this topic was conducted in PubMed and Google Scholar. The result is a non-systematic, narrative review focusing on recent clinical and experimental findings of pain sensitivity in patients with psychosis. Importantly, physical and mental pain are closely connected constructs that may be difficult to differentiate. Our hope is that the review provides some clarity to the field in the specific context of schizophrenia. View Full-Text
Keywords: psychosis; schizophrenia; pain sensitivity; pain stimulus psychosis; schizophrenia; pain sensitivity; pain stimulus
MDPI and ACS Style

González-Rodríguez, A.; Labad, J.; Seeman, M.V. Pain Sensitivity in Schizophrenia Spectrum Disorders: A Narrative Review of Recent Work. Psychiatry Int. 2021, 2, 48-58. https://0-doi-org.brum.beds.ac.uk/10.3390/psychiatryint2010004

AMA Style

González-Rodríguez A, Labad J, Seeman MV. Pain Sensitivity in Schizophrenia Spectrum Disorders: A Narrative Review of Recent Work. Psychiatry International. 2021; 2(1):48-58. https://0-doi-org.brum.beds.ac.uk/10.3390/psychiatryint2010004

Chicago/Turabian Style

González-Rodríguez, Alexandre, Javier Labad, and Mary V. Seeman 2021. "Pain Sensitivity in Schizophrenia Spectrum Disorders: A Narrative Review of Recent Work" Psychiatry International 2, no. 1: 48-58. https://0-doi-org.brum.beds.ac.uk/10.3390/psychiatryint2010004

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