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Advanced Radiotherapy Techniques for Mediastinal Lymphomas: Results from an Italian Survey

Radiation Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy
Radiation Oncology Unit, Azienda Ospedaliero-Universitaria Careggi, 50134 Florence, Italy
Radiation Oncology Department, University and Spedali Civili Hospital, 25123 Brescia, Italy
Radiation Oncology, Fondazione IRCCS Policlinico San Matteo and University of Pavia, 27100 Pavia, Italy
Department of Oncology, University of Torino, 10121 Torino, Italy
Radiation Oncology Unit, Azienda USL-IRCCS di Reggio Emilia, 42121 Reggio Emilia, Italy
Department of Medicine and Surgery and Translational Medicine, Radiotherapy Oncology, Sant’Andrea Hospital, “Sapienza” University, 00031 Rome, Italy
Radiation Oncology Department, IRCCS Ospedale Policlinico San Martino, 16100 Genova, Italy
Department of Radiotherapy, San Gerardo Hospital, 20900 Monza, Italy
Radiotherapy Unit, Department of Oncology, University Hospital of Modena, 41100 Modena, Italy
Medical Physics Department, ASST Spedali Civili Hospital, 25123 Brescia, Italy
Author to whom correspondence should be addressed.
Academic Editor: Carmelo Carlo-Stella
Received: 14 June 2021 / Revised: 21 July 2021 / Accepted: 26 July 2021 / Published: 2 August 2021
(This article belongs to the Section Lymphomas)
Background: Multiple methods have been implemented to limit the impact of radiotherapy on patients affected by mediastinal lymphoma, including breathing control techniques, image-guided radiotherapy (IGRT) and intensity-modulated radiotherapy (IMRT), although the actual diffusion of such techniques is unclear. No surveys have been published to date evaluating the techniques adopted at different centers. Methods: A survey with a dedicated questionnaire was submitted to 195 Italian radiotherapy centers, assessing items regarding the characteristics of the center and clinical practice in the treatment of mediastinal lymphomas. Results: A total of 43 centers (22%) responded, the majority of which were university hospitals (37.2%) or cancer care centers (27.9%). In 95.4% of the centers, IMRT was used in the clinical practice, and the most frequently employed techniques were VMAT (48.8% of centers) and non-rotational IMRT (31.7%). Comparison of multiple plans was performed by 66.7% of the responding centers. Dose constraints for organs at risk were consistently prescribed. IGRT techniques were adopted by 93% of the centers, while breathing control or gating techniques were routinely used by only 25.6% of the centers. A necessity to standardize OAR constraints and define guidelines was perceived by almost all participants. Conclusions: Modern radiotherapy techniques are widely used in the Italian centers, although with heterogeneous characteristics. View Full-Text
Keywords: radiotherapy; lymphoma; survey; IMRT; mediastinal; IGRT radiotherapy; lymphoma; survey; IMRT; mediastinal; IGRT
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MDPI and ACS Style

Di Russo, A.; Simontacchi, G.; Guerini, A.E.; Filippi, A.R.; Levis, M.; Ciammella, P.; De Sanctis, V.; Vagge, S.; Meregalli, S.; De Marco, G.; Lanfranchi, B.; Spiazzi, L.; Buglione, M. Advanced Radiotherapy Techniques for Mediastinal Lymphomas: Results from an Italian Survey. Hemato 2021, 2, 496-504.

AMA Style

Di Russo A, Simontacchi G, Guerini AE, Filippi AR, Levis M, Ciammella P, De Sanctis V, Vagge S, Meregalli S, De Marco G, Lanfranchi B, Spiazzi L, Buglione M. Advanced Radiotherapy Techniques for Mediastinal Lymphomas: Results from an Italian Survey. Hemato. 2021; 2(3):496-504.

Chicago/Turabian Style

Di Russo, Anna, Gabriele Simontacchi, Andrea E. Guerini, Andrea R. Filippi, Mario Levis, Patrizia Ciammella, Vitaliana De Sanctis, Stefano Vagge, Sofia Meregalli, Giuseppina De Marco, Biancaluisa Lanfranchi, Luigi Spiazzi, and Michela Buglione. 2021. "Advanced Radiotherapy Techniques for Mediastinal Lymphomas: Results from an Italian Survey" Hemato 2, no. 3: 496-504.

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