Reprint

Cannabis

Neuropsychiatry and Its Effects on Brain and Behavior

Edited by
February 2021
204 pages
  • ISBN978-3-03943-995-9 (Hardback)
  • ISBN978-3-03943-996-6 (PDF)

This book is a reprint of the Special Issue Cannabis: Neuropsychiatry and Its Effects on Brain and Behavior that was published in

Biology & Life Sciences
Computer Science & Mathematics
Medicine & Pharmacology
Public Health & Healthcare
Summary
Over the years, there has been increasing interest into the public health impact of cannabis use, especially by young adults. This follows the evidence of a growing prevalence of regular cannabis use worldwide, with approximately 200 million users. Recreational cannabis use, especially a frequent use of products with high levels of its main psychoactive ingredient delta-9-tetrahydrocannabinol (Δ 9-THC), can cause dependence and have transient and long-lasting detrimental mental health effects, also negatively impacting cognitive processing and brain function and metabolism. In regular users, the development of tolerance to some of the effects of cannabis, especially the pleasurable ones, may lead to progressively heavier use in order to obtain the same effects in terms of their intensity, with higher health risks. However, the Cannabis Sativa plant contains different chemicals with different potential effects. In this regard, cannabidiol has gained interest because of its potential therapeutic properties, in line with evidence that CBD and Δ9-THC may exhibit opposite effects at the cannabinoid receptor type 1 (CB1), Δ9-THC being a partial agonist and CBD an antagonist/inverse agonist. Different cannabinoids may modulate human brain function and behavior in different ways, with different risk–benefit profiles.
Format
  • Hardback
License
© by the authors
Keywords
delta-9-tetrahydrocannabinol; placebo; cannabis-associated psychosis; schizophrenia; BDNF; CB1; CB2; episodic memory; exercise; African American; black; older adult; marijuana use; cannabis use disorder; cue reactivity; craving; inhibitory control; frontal alpha asymmetry; EEG; cannabinoids; cannabis use; psychotic disorder; genetics; age of onset; clinical high risk; cannabis; memory; functional magnetic resonance imaging; THC; systematic review; cannabis; gyrification; surface area; cortical surface structure; aerobic fitness; gender; delta-9-tetrahydrocannabinol; endocannabinoid system; executive functions; problematic cannabis use; triple network; EEG functional connectivity; eLORETA; resting state; Delta-9-tetrahydrocannabinol; dronabinol; marijuana; randomized controlled trial; opioids; traumatic injury; cannabis; alcohol; adolescents; fMRI; interoception; negative reinforcement; cue reactivity; cannabinoids; migraine: chronic pain; opioids; triptans; disability; n/a