Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.2
3.0
Journals
Animals
Special Issues
Recent Advances in Poultry Respiratory and Immunosuppressive Viral Diseases
share announcement

Recent Advances in Poultry Respiratory and Immunosuppressive Viral Diseases

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".

Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 18039

Special Issue Editors

Prof. Dr. Elena Catelli

E-Mail Website
Guest Editor
Department of Veterinary Medical Sciences, University of Bologna, 40126 Bologna, Italy
Interests: vaccines; vaccine development; marek's disease; avian metapneumovirus; avian coronavirus; infectious bursal disease; newcastle disease; avian influenza; avian viral respiratory diseases; avian immunosuppressive diseases
Special Issues, Collections and Topics in MDPI journals
Dr. Caterina Lupini

E-Mail Website
Guest Editor
Department of Veterinary Medical Sciences, University of Bologna, 40126 Bologna, Italy
Interests: avian viral diseases; vaccines; vaccine development; avian respiratory diseases; avian viral immunosuppressive diseases
Special Issues, Collections and Topics in MDPI journals
Dr. Giulia Mescolini

E-Mail Website
Guest Editor
A.U.S.L. della Romagna - Via Don Eugenio Servadei, 3, 47122 Forlì, FC, Italy
Interests: Marek's disease; avian metapneumovirus; avian coronavirus; infectious bursal disease; avian viral respiratory and immunosuppressive diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Technological innovation has greatly improved the efficiency and the welfare of poultry production, especially in relation to nutrition, housing, and health management.

Despite the great strides made in terms of disease control, respiratory and immunosuppressive viral diseases remain one of the main challenges for the intensively reared poultry, while these infections can cause substantial economic losses themselves, and act as a trigger for even more serious bacterial disease.

We invite original research papers that address recent advances in the etiology, epidemiology, pathobiology, diagnosis, and control by vaccination of viral respiratory and immunosuppressive diseases of poultry. Studies on the major viral infections of poultry as Infectious bronchitis ( Avian coronavirus), Turkey rhinotrachetits and Swallen head disease (Avian metapneumovirus), Infectious Laryngotracheitis (Gallid alphaherpesvirus 1), Newcastle disease (Avian orthoavulavirus 1), Avian Influenza (Influenza A virus), Infectious bursal disease (Infectious bursal disease virus), Chicken infectious anemia (Chicken anemia virus), Marek’s disease (Gallid alphaherpesvirus 2), and Turkey hemorrhagic enteritis (Turkey siadenovirus A) are welcomed.  Minor, or newly observed, respiratory and immunosuppressive viral conditions will be also considered.  Additional topics may include the interaction between different pathogens in experimental or field conditions or the observation of well-known agents in unusual host species

Prof. Elena Catelli
Dr. Caterina Lupini
Dr. Giulia Mescolini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Poultry
  • Epidemiology
  • Pathobiology
  • Vaccines
  • Avian Coronavirus
  • Infectious Laryngotracheitis
  • Newcastle disease
  • Avian influenza
  • Infectious Bursal disease
  • Marek’s Disease

Published Papers (6 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

12 pages, 1833 KiB  
Article
Longitudinal Survey on aMPV Circulation in French Broiler Flocks following Different Vaccination Strategies
by Caterina Lupini, Claudia Maria Tucciarone, Giulia Mescolini, Giulia Quaglia, Giulia Graziosi, Vincent Turblin, Paul Brown, Mattia Cecchinato, Matteo Legnardi, Thomas Delquigny, Stéphane Lemiere, Guillaume Perreul and Elena Catelli
Animals 2023, 13(1), 57; https://0-doi-org.brum.beds.ac.uk/10.3390/ani13010057 - 23 Dec 2022
Viewed by 1457
Abstract
In recent years, the impact of respiratory disease resulting from Avian Metapneumovirus (aMPV) infection has been generally rising in the broiler industry in Europe. In this context, in order to investigate aMPV contribution to the clinical picture and the potential benefits of diversified [...] Read more.
In recent years, the impact of respiratory disease resulting from Avian Metapneumovirus (aMPV) infection has been generally rising in the broiler industry in Europe. In this context, in order to investigate aMPV contribution to the clinical picture and the potential benefits of diversified vaccination strategies compared to nonvaccination policies, a longitudinal monitoring was performed, also evaluating Infectious Bronchitis Virus (IBV) presence. Broiler flocks located in Western France, where aMPV has already proven to be a health and productivity issue, were screened by RT-PCR on rhino-pharyngeal swabs, and the viruses were genetically characterized by sequence analysis. For a more comprehensive picture of aMPV molecular epidemiology and evolution in France, aMPV subtype B strains detected from 1985 to 1998 were sequenced and included in the analysis. The survey confirmed the detection of aMPV subtype B in commercial broiler flocks in France, together with a certain heterogeneity demonstrated by the circulation of more recent and historical French field strains. No IBV field strains were detected. The implementation and evaluation of different management choices and vaccine strategies suggests once again that immunization does not prevent infection but contributes greatly to the containment of the clinical manifestations. Full article
(This article belongs to the Special Issue Recent Advances in Poultry Respiratory and Immunosuppressive Viral Diseases)
►▼ Show Figures

Figure 1

14 pages, 2598 KiB  
Article
Pathogenicity and Transmissibility of Clade 2.3.4.4h H5N6 Avian Influenza Viruses in Mammals
by Cheng Zhang, Huan Cui, Chunmao Zhang, Kui Zhao, Yunyi Kong, Ligong Chen, Shishan Dong, Zhaoliang Chen, Jie Pu, Lei Zhang, Zhendong Guo and Juxiang Liu
Animals 2022, 12(22), 3079; https://0-doi-org.brum.beds.ac.uk/10.3390/ani12223079 - 09 Nov 2022
Viewed by 1793
Abstract
Avian influenza viruses (AIVs) have the potential for cross-species transmission and pandemics. In recent years, clade 2.3.4.4 H5N6 AIVs are prevalent in domestic poultry, posing a threat to the domestic poultry industry and public health. In this study, two strains of H5N6 AIVs [...] Read more.
Avian influenza viruses (AIVs) have the potential for cross-species transmission and pandemics. In recent years, clade 2.3.4.4 H5N6 AIVs are prevalent in domestic poultry, posing a threat to the domestic poultry industry and public health. In this study, two strains of H5N6 AIVs were isolated from chickens in Hebei, China, in 2019: A/chicken/Hebei/HB1907/2019(H5N6) and A/chicken/Hebei/HB1905/2019(H5N6). Phylogenetic analysis showed that both viral HA genes clustered in the 2.3.4.4h clade. Receptor binding analysis showed that the HB1905 strain preferentially binds to α-2,3-linked sialic acid (SA) receptors, while the HB1907 strain preferentially binds to α-2,3- and α-2,6-linked sialic acid (SA) receptors. During early infection, the HB1907 strain is highly replicable in MDCK cells, more so than the HB1905 strain. Pathogenicity assays in mice showed that both viruses could replicate in the lungs without prior adaptation, with HB1907 being more highly pathogenic in mice than the HB1905 strain. Significantly, both the HB1905 and HB1907 strains can be transmitted through direct contact among guinea pigs, but the transmission efficiency of the HB1907 strain through contact between guinea pigs is much greater than that of the HB1905 strain. These results strengthen the need for ongoing surveillance and early warning of H5N6 AIVs in poultry. Full article
(This article belongs to the Special Issue Recent Advances in Poultry Respiratory and Immunosuppressive Viral Diseases)
►▼ Show Figures

Figure 1

11 pages, 1190 KiB  
Article
Occurrence of Chicken Infectious Anemia Virus in Industrial and Backyard Tunisian Broilers: Preliminary Results
by Antonietta Di Francesco, Giulia Quaglia, Daniela Salvatore, Sonia Sakhria, Elena Catelli, Ghaith Bessoussa, Khaled Kaboudi, Noureddine Ben Chehida and Caterina Lupini
Animals 2022, 12(1), 62; https://0-doi-org.brum.beds.ac.uk/10.3390/ani12010062 - 28 Dec 2021
Cited by 3 | Viewed by 2325
Abstract
Chicken infectious anemia virus (CIAV) is an economically important and widely distributed immunosuppressive agent in chickens. This study performed an epidemiological investigation on CIAV circulation in 195 Tunisian broilers, belonging to 13 lots from five industrial farms and in one rural farm. Fifteen [...] Read more.
Chicken infectious anemia virus (CIAV) is an economically important and widely distributed immunosuppressive agent in chickens. This study performed an epidemiological investigation on CIAV circulation in 195 Tunisian broilers, belonging to 13 lots from five industrial farms and in one rural farm. Fifteen animals were detected positive by a VP1 nested PCR. The amplicons were molecularly characterised by complete genome sequencing. All positive samples obtained in this study were from the rural farm, whereas the industrial farms sampled were negative. Nucleotide and amino acid sequence analyses showed a high degree of similarity among the sequences obtained, suggesting the circulation of a single CIAV strain in the positive lot. Phylogenetic analysis based on the CIAV VP1 nucleotide sequence and/or the complete genome showed that the sequences obtained in this study clustered with CIAV strains previously detected in Tunisia, Italy and Egypt, belonging to genogroup II. Our results highlight the need for constant CIAV surveillance in backyard chicken production. Full article
(This article belongs to the Special Issue Recent Advances in Poultry Respiratory and Immunosuppressive Viral Diseases)
►▼ Show Figures

Figure 1

28 pages, 7240 KiB  
Article
Pathogenesis of Velogenic Genotype VII.1.1 Newcastle Disease Virus Isolated from Chicken in Egypt via Different Inoculation Routes: Molecular, Histopathological, and Immunohistochemical Study
by Yassmin EL-Morshidy, Walied Abdo, Ehab Kotb Elmahallawy, Ghada Allam Abd EL-Dayem, Ahmed El-Sawak, Nagwan El-Habashi, Samah M. Mosad, Maha S. Lokman, Ashraf Albrakati and Samah Abou Asa
Animals 2021, 11(12), 3567; https://0-doi-org.brum.beds.ac.uk/10.3390/ani11123567 - 15 Dec 2021
Cited by 7 | Viewed by 3876
Abstract
Newcastle disease virus (NDV) remains a constant threat to the poultry industry. There is scarce information concerning the pathogenicity and genetic characteristics of the circulating velogenic Newcastle disease virus (NDV) in Egypt. In the present work, NDV was screened from tracheal swabs collected [...] Read more.
Newcastle disease virus (NDV) remains a constant threat to the poultry industry. There is scarce information concerning the pathogenicity and genetic characteristics of the circulating velogenic Newcastle disease virus (NDV) in Egypt. In the present work, NDV was screened from tracheal swabs collected from several broiler chicken farms (N = 12) in Dakahlia Governorate, Egypt. Real-time reverse transcriptase polymerase chain reaction (RRT-PCR) was used for screening of velogenic and mesogenic NDV strains through targeting F gene fragment amplification, followed by sequencing of the resulting PCR products. The identified strain, namely, NDV-CH-EGYPT-F42-DAKAHLIA-2019, was isolated and titrated in the allantoic cavity of 10 day old specific pathogen-free (SPF) embryonated chicken eggs (ECEs), and then their virulence was determined by mean death time (MDT) and intracerebral pathogenicity index (ICPI). The pathogenicity of the identified velogenic NDV strain was also assessed in 28 day old chickens using different inoculation routes as follows: intraocular, choanal slit, intranasal routes, and a combination of both intranasal and intraocular routes. In addition, sera were collected 5 and 10 days post inoculation (pi) for the detection of NDV antibodies by hemagglutination inhibition test (HI), and tissue samples from different organs were collected for histopathological and immunohistochemical examination. A series of different clinical signs and postmortem lesions were recorded with the various routes. Interestingly, histopathology and immunohistochemistry for NDV nucleoprotein displayed widespread systemic distribution. The intensity of viral nucleoprotein immunolabeling was detected within different cells including the epithelial and endothelium lining, as well as macrophages. The onset, distribution, and severity of the observed lesions were remarkably different between various inoculation routes. Collectively, a time-course comparative pathogenesis study of NDV infection demonstrated the role of different routes in the pathogenicity of NDV. The intranasal challenge was associated with a prominent increase in NDV lesions, whereas the choanal slit route was the route least accompanied by severe NDV pathological findings. Clearly, the present findings might be helpful for implementation of proper vaccination strategies against NDV. Full article
(This article belongs to the Special Issue Recent Advances in Poultry Respiratory and Immunosuppressive Viral Diseases)
►▼ Show Figures

Figure 1

13 pages, 1405 KiB  
Article
Genetic Heterogeneity among Chicken Infectious Anemia Viruses Detected in Italian Fowl
by Giulia Quaglia, Giulia Mescolini, Elena Catelli, Giacomo Berto, Filippo Muccioli and Caterina Lupini
Animals 2021, 11(4), 944; https://0-doi-org.brum.beds.ac.uk/10.3390/ani11040944 - 27 Mar 2021
Cited by 8 | Viewed by 2557
Abstract
Chicken infectious anemia virus (CIAV) is a pathogen of chickens associated with immunosuppression and with a disease named chicken infectious anemia. The present survey reports an epidemiological study on CIAV distribution in Italian broiler, broiler breeder and backyard chicken flocks. Twenty-five strains were [...] Read more.
Chicken infectious anemia virus (CIAV) is a pathogen of chickens associated with immunosuppression and with a disease named chicken infectious anemia. The present survey reports an epidemiological study on CIAV distribution in Italian broiler, broiler breeder and backyard chicken flocks. Twenty-five strains were detected by a specifically developed nested PCR protocol, and molecularly characterized by partial VP1 gene or complete genome sequencing. Viral DNA amplification was successfully obtained from non-invasive samples such as feathers and environmental dust. Sequence and phylogenetic analysis showed the circulation of field or potentially vaccine-derived strains with heterogeneous sequences clustered into genogroups II, IIIa, and IIIb. Marker genome positions, reported to be correlated with CIAV virulence, were evaluated in field strains. In conclusion, this is the first survey focused on the molecular characteristics of Italian CIAVs, which have proved to be highly heterogeneous, implementing at the same time a distribution map of field viruses worldwide. Full article
(This article belongs to the Special Issue Recent Advances in Poultry Respiratory and Immunosuppressive Viral Diseases)
►▼ Show Figures

Figure 1

20 pages, 4793 KiB  
Article
Molecular Characterization of Velogenic Newcastle Disease Virus (Sub-Genotype VII.1.1) from Wild Birds, with Assessment of Its Pathogenicity in Susceptible Chickens
by Khaled Saad Abd Elfatah, Moshira Abas Elabasy, Faris El-khyate, Ehab Kotb Elmahallawy, Samah M. Mosad, Fatma A. El-Gohary, Walied Abdo, Ashraf Al-Brakati, Mohamed G. Seadawy, Abd Elnaby Tahoon and Abd Elgalil El-Gohary
Animals 2021, 11(2), 505; https://0-doi-org.brum.beds.ac.uk/10.3390/ani11020505 - 15 Feb 2021
Cited by 21 | Viewed by 4366
Abstract
Newcastle disease (ND) is considered to be one of the most economically significant avian viral diseases. It has a worldwide distribution and a continuous diversity of genotypes. Despite its limited zoonotic potential, Newcastle disease virus (NDV) outbreaks in Egypt occur frequently and result [...] Read more.
Newcastle disease (ND) is considered to be one of the most economically significant avian viral diseases. It has a worldwide distribution and a continuous diversity of genotypes. Despite its limited zoonotic potential, Newcastle disease virus (NDV) outbreaks in Egypt occur frequently and result in serious economic losses in the poultry industry. In this study, we investigated and characterized NDV in wild cattle egrets and house sparrows. Fifty cattle egrets and fifty house sparrows were collected from the vicinity of chicken farms in Kafrelsheikh Governorate, Egypt, which has a history of NDV infection. Lung, spleen, and brain tissue samples were pooled from each bird and screened for NDV by real-time reverse transcriptase polymerase chain reaction (RRT-PCR) and reverse transcriptase polymerase chain reaction (RT-PCR) to amplify the 370 bp NDV F gene fragment. NDV was detected by RRT-PCR in 22 of 50 (44%) cattle egrets and 13 of 50 (26%) house sparrows, while the conventional RT-PCR detected NDV in 18 of 50 (36%) cattle egrets and 10 of 50 (20%) of house sparrows. Phylogenic analysis revealed that the NDV strains identified in the present study are closely related to other Egyptian class II, sub-genotype VII.1.1 NDV strains from GenBank, having 99.7–98.5% identity. The pathogenicity of the wild-bird-origin NDV sub-genotype VII.1.1 NDV strains were assessed by experimental inoculation of identified strains (KFS-Motobas-2, KFS-Elhamoul-1, and KFS-Elhamoul-3) in 28-day-old specific-pathogen-free (SPF) Cobb chickens. The clinical signs and post-mortem changes of velogenic NDV genotype VII (GVII) were observed in inoculated chickens 3 to 7 days post-inoculation, with 67.5–70% mortality rates. NDV was detected in all NDV-inoculated chickens by RRT-PCR and RT-PCR at 3, 7, and 10 days post-inoculation. The histopathological findings of the experimentally infected chickens showed marked pulmonary congestion and pneumonia associated with complete bronchial stenosis. The spleen showed histocytic cell proliferation with marked lymphoid depletion, while the brain had malacia and diffuse gliosis. These findings provide interesting data about the characterization of NDV in wild birds from Egypt and add to our understanding of their possible role in the transmission dynamics of the disease in Egypt. Further research is needed to explore the role of other species of wild birds in the epidemiology of this disease and to compare the strains circulating in wild birds with those found in poultry. Full article
(This article belongs to the Special Issue Recent Advances in Poultry Respiratory and Immunosuppressive Viral Diseases)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-6
Back to TopTop