Host-Pathogen Interactions in Acinetobacter baumannii Infection
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Genetic and Biochemical Studies of Antibiotic Activity and Resistance".
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 335
Special Issue Information
Acinetobacter baumannii causes severe and often fatal healthcare (nosocomial and community-acquired)-associated infections. The bacterium is categorized as a critical threat multidrug-resistant (MDR) pathogen by the World Health Organization and the US Center for Disease Control and Prevention. The majority of current A. baumannii research has focused on its molecular epidemiology and the patterns and mechanisms of antimicrobial resistance, whereas our understanding of virulence and immunopathogenesis of A. baumannii infection is significantly lagging behind. Therefore, there is an urgent need for new knowledge on how A. baumannii colonize, transmit, and infect the host and how the host immune system responds to the infection at both systemic and tissue levels. In addition, there is a strong interest in understanding the strategies used by A. baumannii to escape host immune responses. Such knowledge is critical for identifying novel therapeutic targets and developing knowledge-driven strategies for infection control.
The aim of this Special Issue is to provide insight into the complex cellular and molecular interactions of A. baumannii with the host and its impact on the outcome of infection. More specifically, we wish to invite Original Research articles, Reviews, and Commentaries that address the following topics:
- Novel bacterial virulence factors, tissue tropism, and pathogenesis mechanisms;
- Crosstalk between baumannii and other microbes in the infection process and in polymicrobial infections;
- Host signaling in the regulation of the virulence and metabolisms of baumannii;
- Resistance to and evasion of the host immune response by baumannii;
- Host immune status on the susceptibility to baumannii infection;
- Novel methods and systems for studying host-baumannii interaction.
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Acinetobacter
- pathogenesis
- virulence
- transcriptional regulation
- innate immunity
- antibiotics
- antimicrobial resistance
