Special Issue "New Biomolecules and Drug Delivery Systems as Alternatives to Conventional Antibiotics"
Deadline for manuscript submissions: 31 December 2021.
Interests: biomaterials; antimicrobial agents; surface functionalization; polymer processing; biomolecules
Special Issues and Collections in MDPI journals
Special Issue in Processes: Advances of Antimicrobial in Bioengineering
Special Issue in Polymers: Extraction of Cellulose-Based Polymers from Textile Wastes
Special Issue in Nanomaterials: Biobased Nanoscale Drug Delivery Systems
Special Issue in Biomolecules: Bio-Based Co-Adjuvant Systems for Infection Control
Special Issue in Nanomaterials: Untargeted versus Targeted Antimicrobial Nanomedicines
Special Issue in International Journal of Molecular Sciences: Biomolecule-Based Biomaterials and Their Application in Drug Delivery Systems
Special Issue in International Journal of Molecular Sciences: Frontiers in Antimicrobial Biomaterials
New approaches to deal with the growing concern associated with antibiotic-resistant bacteria are in great demand. For many years, antibiotics have been widely employed to treat infections. However, their excessive consumption and misuse have accelerated the rise of antibiotic-resistant microorganisms, which constitute one of the dominant challenges to global health. The antibiotic crisis is now a general concern and alternative biomolecules or drug delivery systems to treat infections are, therefore, urgently needed. From natural extracts to traditional medicine remedies, to newly engineered nanocapsules and nanoparticles to bio-based, biodegradable delivery platforms, many systems to fight infections have been proposed.
This Special Issue seeks manuscript submissions that further our understanding of the antimicrobial action of specialized biomolecules, recently engineered or chemically modified from their ancient origins, as alternatives to conventional antibiotics. Submissions on the response of microorganisms to these agents, their contribution to infection control, and prevention of serious conditions/illnesses from occurring or evolving, are especially encouraged. Publications that aim at a deeper understanding of the synergistic effects between different biomolecules and/or biomaterials (as delivery platforms) in infected wound care and establish their advantageous performance as a new step towards the resolution of the antibiotic crisis are also very welcome.
Dr. Helena P. Felgueiras
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Antimicrobial agents
- Infection control
- Baceria resistance
- Natural extracts
- Biomaterials functionalization
- Biological delivery systems
- Local and systemic drug administration
- Antibiotics world crisis
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Recent advances in fiber-hydrogel composites for wound healing and drug delivery systems
Marta O. Teixeira, Joana C. Antunes and Helena P. Felgueiras*
Centre for Textile Science and Technology (2C2T), Department of Textile Engineering, University of Minho, Campus of Azurém, 4800-058 Guimarães, Portugal; [email protected] (M.O.T); [email protected] (J.C.A.); [email protected] (H.P.F.)
*Correspondence: [email protected]; Tel.: +351-253-510-283; Fax: +351-253-510-293
In the last decades, much research has been done to fasten wound healing and target-direct drug delivery. Hydrogel-based scaffolds have been a recurrent solution in both cases, with some reaching already the market, even though their mechanical stability remains a challenge. To overcome this limitation, reinforcement of hydrogels with fibers has been explored. The structural resemblance of fiber-hydrogel composites to natural tissues has been a driving force for the optimization and exploration of these systems in biomedicine. Indeed, the combination of hydrogel-forming techniques and fiber spinning approaches has been crucial in the development of scaffolding systems with improved mechanical strength and medicinal properties. In this review, a comprehensive overview of the recently developed fiber-hydrogel composite strategies for wound healing and drug delivery is provided. The methodologies employed in fiber and hydrogel production are also highlighted, together with the most compatible polymer combinations, as well as drug incorporation approaches creating stimuli-sensitive and triggered drug release towards an enhanced host response.