Special Issue "Molecular Mechanisms of Antibiotic Resistance in Staphylococcus aureus"
Deadline for manuscript submissions: 1 October 2021.
Interests: antimicrobials and resistance mechanisms; Staphylocococcus aureus; host immune responses
Interests: antimicrobial resistance; bacterial virulence; biofilms; Staphylococcus aureus; Acinetobacter baumannii
Since their discovery, antibiotics have revolutionsed medicine, resulting in a major decline in infection related morbidity and mortality. In the last eight decades, the widespread use of antibiotics, has resulted in the emergence of antimicrobial resistance (AMR). With a post-antibiotic era fast approaching, the rapid rise of AMR has now become one of the greatest threats to human health. Staphylococcus aureus is particularly concerning as it has both an arsenal of virulence factors as well as the ability to acquire resistance to most antibiotics. The clinical use of methicillin has led to the appearance of methicillin resistant S. aureus (MRSA), not only in the traditional clinical setting but also in the community setting, leading to infections in people without predisposing risk factors. Treatment of MRSA infections increasingly relies on last resort antibiotics but further resistance to the last line antibiotics is alarming.
Elucidating the molecular mechanisms behind these complex resistance phenotypes is crucial for novel therapeutic strategies that can circumvent AMR development. Application of new technology such as next-generation sequencing and cryo-eletron microscopy also provides valuable insights into AMR. In this Special Issue we seek manuscript submissions that further our undertanding of the molecular mechanisms of resistance in staphylococci. Submissions addressing resistance to non-pharmaceutical treatments such as phage therapy are also welcomed.
Dr. Jhih-Hang Jiang
Dr. Xenia Kostoulias
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- antibiotic resistance
- comparative genomics
- bacterial virulence
- host immune responses