Special Issue "Phytocompounds with Antimicrobial Activity: from Discovery to Application"

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Plant-Derived Antibiotics".

Deadline for manuscript submissions: 16 December 2021.

Special Issue Editors

Dr. Roberta Colicchio
E-Mail Website
Guest Editor
Department of Molecular Medicine and Medical Biotechnology, Universita degli Studi di Napoli Federico II, Naples, Italy
Interests: host-parasite interaction; microbial pathogenicity; antimicrobial peptides; antimicrobial activity of phytocompounds; Rifampicin resistance; Neisseria meningitidis
Dr. Chiara Pagliuca
E-Mail Website
Guest Editor
Department of Molecular Medicine and Medical Biotechnology, Universita degli Studi di Napoli Federico II, Naples, Italy
Interests: microbiota; neisseria; in vivo infection model; antimicrobial natural extracts, characterization of pathogenic bacteria

Special Issue Information

Dear Colleagues,

Today, infections associated with multidrug-resistant (MDR) bacteria still represent a great challenge yet to be treated due to limited therapeutic options, thus requiring alternative antimicrobial strategies. In this regard today, a wide range of new drugs are being derived from plant metabolites. Any single plant indeed represents a library of hundreds to thousands of architecturally and stereochemically complex chemicals, termed phytochemicals. Therefore, in recent years, to counteract antimicrobial resistance, phytocompounds with antimicrobial activity are widely recommended by the experts. Their use, in combination with the conventional commercial antibiotics, exhibits superior antimicrobial activities. Moreover, the membrane proteins that were accountable for antibiotic efflux can be effectively treated by antimicrobial phytocompounds that, therefore, could represent new weapons in the battle against intractable infectious diseases. This Special Issue seeks submissions that further our understanding of new, more active phytocompounds with antimicrobial activity focusing on the discovery and development of new molecules and their potential applications.

Dr. Roberta Colicchio
Dr. Chiara Pagliuca
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Phytocompounds
  • Antibacterial activity
  • Multidrug-resistant (MDR) bacteria
  • Modulatory activity
  • Bioactive extracts
  • Synergistic effect

Published Papers

This special issue is now open for submission.
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