Antipathogenic Effects and Their Molecular Imaging in Dental and Orthopedic Research

A special issue of Antibiotics (ISSN 2079-6382).

Deadline for manuscript submissions: closed (30 August 2021) | Viewed by 3355

Special Issue Editors

Department of Dental Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602-8566, Japan
Interests: biomaterials; dental medicine; bio-imaging
Faculty of Materials Science and Engineering, Kyoto Institute of Technology, Kyoto, Japan
Interests: bioceramics; Raman spectroscopy and imaging; orthopedic and dental medicine
Medical Mycology, Graduate School of Medicine, Teikyo University, Tokyo, Japan
Interests: pathogenic fungi; molecular diagnosis; mycosis

Special Issue Information

Dear Colleagues,

Biomaterials for dentures, dental implants, artificial joints, cements, etc., used in dentistry and orthopedics should allow recovery of basic functions, be resistant to infections from a variety of pathogens (including bacteria and fungi), and demonstrate benign interactions with human cells.

 The latest generation of molecular imaging techniques (fluorescence imaging, positron emission tomography, single photon emission computed tomography, Raman imaging, etc.) enables researchers to visualize the location of the infection and to scrutinize the metabolism of pathogens (including viruses, parasites, bacteria, and fungi) in their interaction with biomaterials. Such microscopic insights are key to understanding the molecular mechanisms of infection and defense.

This Special Issue welcomes research on new antibacterial materials and molecular imaging that visualizes the molecular mechanisms of infection in dental and orthopedic research.

Dr. Tetsuya Adachi
Prof. Giuseppe Pezzotti
Prof. Koichi Makimura
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antipathogenic materials
  • molecular imaging
  • antimicrobial resistance
  • antiviral resistance
  • antibacterial activity
  • antifungal activity
  • disinfectants
  • dental materials
  • orthopedic materials

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

13 pages, 13287 KiB  
Article
Antibacterial and Antifungal Properties of Composite Polyethylene Materials Reinforced with Neem and Turmeric
by Thefye P. M. Sunthar, Elia Marin, Francesco Boschetto, Matteo Zanocco, Hirofumi Sunahara, Raviduth Ramful, Kaeko Kamei, Wenliang Zhu and Giuseppe Pezzotti
Antibiotics 2020, 9(12), 857; https://0-doi-org.brum.beds.ac.uk/10.3390/antibiotics9120857 - 30 Nov 2020
Cited by 4 | Viewed by 2679
Abstract
With the increased scientific interest in green technologies, many researches have been focused on the production of polymeric composites containing naturally occurring reinforcing particles. Apart from increasing mechanical properties, these additions can have a wide range of interesting effects, such as increasing the [...] Read more.
With the increased scientific interest in green technologies, many researches have been focused on the production of polymeric composites containing naturally occurring reinforcing particles. Apart from increasing mechanical properties, these additions can have a wide range of interesting effects, such as increasing the resistance to bacterial and fungal colonization. In this work, different amounts of two different natural products, namely neem and turmeric, were added to polyethylene to act as a natural antibacterial and antifungal product for food packaging applications. Microscopic and spectroscopic characterization showed that fractions of up to 5% of these products could be dispersed into low-molecular weight polyethylene, while higher amounts could not be properly dispersed and resulted in an inhomogeneous, fragile composite. In vitro testing conducted with Escherichia coli, Staphylococcus aureus, and Candida albicans showed a reduced proliferation of pathogens when compared to the polyethylene references. In particular, turmeric resulted in being more effective against E. coli when compared to neem, while they had similar performances against S. aureus. Against C. albicans, only neem was able to show a good antifungal behavior, at high concentrations. Tensile testing showed that the addition of reinforcing particles reduced the mechanical properties of polyethylene, and in the case of turmeric, it was further reduced by UV irradiation. Full article
Show Figures

Figure 1

Back to TopTop