Special Issue "Synthesis and Pharmacokinetics of Antibiotics"
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: closed (30 November 2020).
Interests: Biological active compounds: antimicrobials; antiarrhythmics; anticancers; melatonergic drugs; voltage-gated sodium channel blockers
Special Issues and Collections in MDPI journals
The development of antibiotics has contributed greatly to increases in life expectancy and improvements in the quality of life. However, many decades after the first patients were treated with antibiotics, bacterial infections have again become a threat. Unfortunately, the development of multidrug resistance by common pathogens has seriously limited the efficacy of antibiotic therapies. Therefore, there is an urgent medical need for the development of new effective antibiotics that are refractory to most common mechanisms of bacterial resistance or that may restrain or inhibit the mechanisms of resistance. Recently, some delivery systems have proved particularly effective as antimicrobial carriers due to their ability to carry out targeted drug delivery at active sites, reduced drug resistance and side effects, and increased therapeutic index.
This Special Issue of Antibiotics aims to present a collection of the latest research in this field including, but not limited to, the following topics:
- The design and synthesis of antimicrobial agents with novel scaffolds;
- Promising new classes of antibiotics acting on novel targets;
- The development of new synthetic approaches starting both from natural and synthetic compounds;
- Structural modifications of antimicrobial natural products for the identification and development of novel antibacterial agents;
- The synthesis of antibiotic analogues with improved pharmacokinetic properties;
- Delivery systems for targeted antimicrobial therapies.
Dr. Alessia Carocci
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Synthesis of antimicrobial agents
- Antibiotics targeted delivery systems
- Pharmacokinetic of antibiotics
- New molecular target for antimicrobial therapy