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Special Issue Editor

Dr. Carmelita G. Frondoza

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Guest Editor

Department of Orthopaedic Surgery, and School of Public Health, Department of Molecular Microbiology and Immunology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA
Interests: in vitro models for disease; tissue repair/regeneration; osteoarthritis; nutraceuticals

Special Issue Information

Dear Colleagues,

Reactive oxygen species (ROS) are highly reactive molecules that play important roles in cellular functions in animals and humans. When present in excess, ROS are cytotoxic. Under normal physiologic conditions, the levels of these reactive molecules are regulated by the body’s antioxidant system. Oxidative stress results when the production of ROS exceeds the capacity of neutralizing antioxidants to detoxify excess ROS. Oxidative stress has been linked to a wide range of pathophysiological conditions, including inflammatory disorders, joint, cardiovascular, neurological diseases, metabolic disease such as diabetes mellitus, cancer, and aging. Some pharmacologic agents are reported to be efficacious in counteracting the adverse effects of oxidative stress. However, experimental and clinical studies have not provided consistent confirmatory evidence for the antioxidative stress efficacy of these drugs. Scientific interest has turned to non-pharmacologic agents as alternative therapies. This special issue focuses on plant-based agents as candidates to mitigate oxidative stress in aging and disease.

Dr. Carmelita Frondoza
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

Reactive oxygen species
Oxidative stress
Plant-derived antioxidants

Published Papers (1 paper)

Research

16 pages, 1706 KiB

Open AccessArticle

Young Shoots of White and Red Headed Cabbages Like Novel Sources of Glucosinolates as Well as Antioxidative Substances

by Joanna Kapusta-Duch and Barbara Kusznierewicz

Antioxidants 2021, 10(8), 1277; https://0-doi-org.brum.beds.ac.uk/10.3390/antiox10081277 - 12 Aug 2021

Cited by 8 | Viewed by 2331

Abstract

Most literature data indicate that the diet rich in plant products reduces the risk of developing chronic non-communicable diseases and cancer. Brassica vegetables are almost exclusively synthesizing glucosinolates. Glucosinolates are higher in sprouts than in mature plants, being related to the activity of the specific myrosinase involved in the degradation of glucosinolates during developmental stages. This study compares the content of total glucosinolates with their profile and, rare in the literature, also with products of their degradation. Average amounts of total glucosinolates in young shoots of white and red headed cabbage were 26.23 µmol/g d.m. and 27.93 µmol/g d.m., respectively. In addition, antioxidative properties of 21-day-old shoots of white and red headed cabbage were assessed. The area of negative peaks after post-column derivatization with the ABTS reagent, indicating antioxidant activity of young red cabbage shoots, was 20185, compared to the value determined for young white cabbage shoots (3929). The results clearly indicate that, regardless of the vegetable species, young shoots of white and red headed cabbage can be an important source of bioactive substances in the diet, thus being an important element of cancer chemoprevention. Full article

(This article belongs to the Special Issue Non-pharmaceutical Antioxidant Agents for Animal and Human Health)

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