Oxidative Stress and Neuroinflammation in Neurological and Neurodegenerative Disorders
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (20 September 2022) | Viewed by 52228
Special Issue Editors
Interests: mitochondria; Parkinson’s disease; neuroinflammation; nerve growth factor; neuronal differentiation
Interests: neuroinflammation; astrocytes; synaptic plasticity; nerve growth factor; vagus nerve stimulation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Age-related increases in oxidative stress and neuroinflammation are common hallmarks of chronic neurodegenerative disorders, such as Alzheimer’s (AD) and Parkinson’s (PD) diseases. Accumulation of reactive oxygen species (ROS) is a natural consequence of the neuronal oxidative metabolism and may overwhelm the antioxidant defenses, thus leading to oxidation of cellular components, mitochondrial dysfunction, redox dysregulation, and alteration of energy metabolism. On the other hand, neurodegeneration is characterized by neuroinflammation, disruption of astroglial function, and mechanisms of maladaptive plasticity. Moreover, as part of the blood–brain barrier, astrocytes play an essential role in neurovascular coupling and neuronal metabolism.
We invite you to submit your contribution as an original research or a review article to this Special Issue, which aims to collect current knowledge concerning mechanisms of oxidative stress and neuroinflammation and their impact on neuronal and glial function in aging and neurodegenerative disorders.
Dr. Anna Maria Colangelo
Prof. Dr. Michele Papa
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- Aging
- Oxidative stress
- Mitochondria
- Metabolism
- Neuroinflammation
- Astrocytes
- Microglia
- Maladaptive plasticity
- Neurodegeneration
- Neuroprotection