Dear Colleagues,

Over recent years, a greater understanding has been obtained surrounding the sole and combined abilities of nutritional supplementation and lifestyle factors to influence chronic low-grade inflammation and oxidative stress. However, a more detailed understanding is required to optimise approaches. As inflammation and oxidative stress responses are themselves very complex and multi-faceted processes, further information is required to decipher the underlying mechanisms of how dietary and lifestyle changes, independently or in combination with each other, influence these processes. Importantly, a key lifestyle factor to consider is physical (in)activity. This is of relevance from both a health perspective, e.g., considering the association between chronic low-grade inflammation and oxidative stress and multiple clinical conditions, and an athletic perspective, e.g., considering the undulating periods of stress experienced by athletes related to optimal performance and recovery. Therefore, the importance of physical (in)activity as a key lifestyle characteristic that requires further exploration alongside dietary supplementation cannot be overstated. As a result, additional benefits could be experienced by individuals from a combined diet and lifestyle approach, over and above those obtained from these factors individually.

After the sucess of the previous Special Issue "Exercise and Inflammation", this Special Issue will include both original research papers and reviews relating to the effects of nutritional supplementation and lifestyle factors on subsequent inflammatory and antioxidant responses. Articles involving human and/or animal models are welcome. Relevant and acceptable topics include, but are not limited to, the following examples: phenotypical and physiological effects of dietary interventions, e.g., pre/probiotics, chronic low-carbohydrate and high-fat diets, effects of nutraceuticals, such as sulforaphane, Montmorency tart cherry juice, beetroot juice, and phytochemical-rich food supplementation. The evaluation of the role of these factors in exercise adaptation and physical (in)activity will be favourably considered.

Prof. Dr. Katsuhiko Suzuki
Dr. Llion Roberts
Guest Editors

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