Cellulose Nanocrystals (CNCs) as Versatile Material for the Biomedical Field

A special issue of Applied Nano (ISSN 2673-3501).

Deadline for manuscript submissions: closed (15 February 2022) | Viewed by 4252

Special Issue Editors


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Guest Editor
Department of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy
Interests: glycoscience; drug discovery; nanoparticles; drug delivery

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Guest Editor
University of Milano-Bicocca, dep. of Earth and Environmental Sciences
Interests: Organic Chemistry of Lignocellulosic Materials

Special Issue Information

Dear Colleagues,

In recent years, nanotechnology and nanomaterials have seen an exponential outburst in the biomedical field, allowing a breakthrough in both therapeutic approaches and in the development of new devices. Among the many nanoscale materials, cellulose nanocrystals have unique characteristics and have already shown very promising properties in the biomedical field. In addition, CNCs are biocompatible, biodegradable, and available on a large scale, unlike many other materials proposed for analogue applications. For this reason, we would like to propose a Special Issue centered on the topic “Cellulose nanocrystals (CNCs) as versatile material for the biomedical field.”

100% discount of Article Processing Charge will apply to the submissions accepted for publication in this Special Issue.

Prof. Dr. Barbara La Ferla
Dr. Luca Zoia
Guest Editors

Manuscript Submission Information

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Published Papers (1 paper)

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Research

10 pages, 1980 KiB  
Article
Binary Biocompatible CNC–Gelatine Hydrogel as 3D Scaffolds Suitable for Cell Culture Adhesion and Growth
by Luca Zoia, Anna Binda, Laura Cipolla, Ilaria Rivolta and Barbara La Ferla
Appl. Nano 2021, 2(2), 118-127; https://0-doi-org.brum.beds.ac.uk/10.3390/applnano2020010 - 24 May 2021
Cited by 2 | Viewed by 3375
Abstract
Binary nano-biocomposite 3D scaffolds of cellulose nanocrystals (CNCs)—gelatine were fabricated without using chemical crosslinking additives. Controlled oxidative treatment allowed introducing carboxyl or carbonyl functionalities on the surface of CNCs responsible for the crosslinking of gelatine polymers. The obtained composites were characterized for their [...] Read more.
Binary nano-biocomposite 3D scaffolds of cellulose nanocrystals (CNCs)—gelatine were fabricated without using chemical crosslinking additives. Controlled oxidative treatment allowed introducing carboxyl or carbonyl functionalities on the surface of CNCs responsible for the crosslinking of gelatine polymers. The obtained composites were characterized for their physical-chemical properties. Their biocompatibility towards different cell cultures was evaluated through MTT and LDH assays, cellular adhesion and proliferation experiments. Gelatine composites reinforced with carbonyl-modified CNCs showed the most performing swelling/degradation profile and the most promising adhesion and proliferation properties towards cell lines, suggesting their potential application in the field of tissue engineering. Full article
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