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Applied Sciences
Special Issues
3D Printing for Orthopaedics
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3D Printing for Orthopaedics

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Materials Science and Engineering".

Deadline for manuscript submissions: closed (30 June 2021) | Viewed by 5059

Special Issue Editors

Dr. Saber AminYavari

E-Mail Website
Guest Editor
Department of Orthopedics, University Medical Center Utrecht, Utrecht, The Netherlands
Interests: surface bio-functionalization; additive manufacturing and prevention of implant failures
Special Issues, Collections and Topics in MDPI journals
Dr. Miguel Dias Castilho

E-Mail Website
Guest Editor
Department of Orthopedics, University Medical Center Utrecht, Utrecht, The Netherlands and Orthopaedic Biomechanics, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands
Interests: additive manufacturing; biomaterials design and mechanics of materials

Special Issue Information

Dear Colleagues,

3D printing technologies have recently evolved to treat different musculoskeletal diseases and tissue damages for orthopedic patients worldwide. Unlike in conventional processing routes, varying the design from one 3D-printed specimen to the next does not result in substantial cost increase, rendering tailor-made designs feasible. Nonetheless, the exploration of 3D printing technologies to create implants with locally tuned material compositions and intricate microstructures that can capture functional properties of musculoskeletal tissues has only recently started. Typically, state-of-the-art permanent implants provide mechanical support but lack biological adaptive properties, while resorbable implants have improved biological properties but typically lack mechanical stability. To extend our current knowledge, important issues such as advances and challenges in 3D printing techniques, emerging bio-fabrication technologies, porous and biodegradable implants, and applications of 3D printing in in vitro predictive models still need to be deeply investigated.

This Special Issue aims to highlight recent strategies in 3D printing for orthopedic biomaterials, and we cordially invite researchers to contribute with original research article, communication or review papers accordingly.

Dr. Miguel Dias Castilho
Dr. Saber AminYavari
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • 3D printing
  • emerging bio-fabrication technologies
  • musculoskeletal diseases
  • patient-specific implants
  • multifunctional biomaterials

Published Papers (1 paper)

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Research

12 pages, 4369 KiB  
Article
Patient-Specific 3-Dimensional Printing Titanium Implant Biomechanical Evaluation for Complex Distal Femoral Open Fracture Reconstruction with Segmental Large Bone Defect: A Nonlinear Finite Element Analysis
by Kin Weng Wong, Chung Da Wu, Chi-Sheng Chien, Cheng-Wei Lee, Tai-Hua Yang and Chun-Li Lin
Appl. Sci. 2020, 10(12), 4098; https://0-doi-org.brum.beds.ac.uk/10.3390/app10124098 - 14 Jun 2020
Cited by 5 | Viewed by 4386
Abstract
This study proposes a novel titanium 3D printing patient-specific implant: a lightweight structure with enough biomechanical strength for a distal femur fracture with segmental large defect using nonlinear finite element (FE) analysis. CT scanning images were processed to identify the size and shape [...] Read more.
This study proposes a novel titanium 3D printing patient-specific implant: a lightweight structure with enough biomechanical strength for a distal femur fracture with segmental large defect using nonlinear finite element (FE) analysis. CT scanning images were processed to identify the size and shape of a large bone defect in the right distal femur of a young patient. A novel titanium implant was designed with a proximal cylinder tube for increasing mechanical stability, proximal/distal shells for increasing bone ingrowth contact areas, and lattice mesh at the outer surface to provide space for morselized cancellous bone grafting. The implant was fixed by transverse screws at the proximal/distal host bone. A pre-contoured locking plate was applied at the lateral site to secure the whole construct. A FE model with nonlinear contact element implant-bone interfaces was constructed to perform simulations for three clinical stages under single leg standing load conditions. The three stages were the initial postoperative period, fracture healing, and post fracture healing and locking plate removal. The results showed that the maximum implant von Mises stress reached 1318 MPa at the sharp angles of the outer mesh structure, exceeding the titanium destruction value (1000 MPa) and requiring round mesh angles to decrease the stress in the initial postoperative period. Bone stress values were found decreasing all the way from the postoperative period to fracture healing and locking plate removal. The overall construct deformation value reached 4.8 mm in the postoperative period, 2.5 mm with fracture healing assisted by the locking plate, and 2.1 mm after locking plate removal. The strain value at the proximal/distal implant-bone interfaces were valuable in inducing bone grafting in the initial postoperative period. The proposed patient-specific 3D printed implant is biomechanically stable for treating distal femoral fractures with large defect. It provides excellent lightweight structure, proximal/distal bone ingrowth contact areas, and implant rounded outer lattice mesh for morselized cancellous bone grafting. Full article
(This article belongs to the Special Issue 3D Printing for Orthopaedics)
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