Applications of Biophotonics in Biology and Medicine

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: closed (30 September 2021) | Viewed by 2142

Special Issue Editor


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Guest Editor
Laboratory of Biophotonics and Applied Biophysics, National Technical University of Athens, 999028 Athens, Greece
Interests: biophotonics; fluorescence imaging microscopy; atomic force microscopy of biomolecules

Special Issue Information

Dear Colleagues,

This Special Issue on “Applications of Biophotonics in Biology and Medicine” contains papers that represent the latest developments in biophotonics technology and sciences for applications in a wide range of biology, life sciences, therapeutics, and diagnostics.

The Special Issue will highlight new research in laser–tissue interaction, imaging and analysis of biomolecules, cells and tissues, 3D and multidimensional microscopy, single molecule spectroscopy, nano/biophotonics such as nanoscale imaging and sensing, markers, nanoparticles microscopy, atomic force microscopy of biomolecules and molecular probes.

In medicine, new trends of Biophotonics to develop innovative systems in neuropathologies, endoscopic microscopy, oncology, photomodulation therapy, dermatology, cardiovascular, optical biopsy, and optical coherence tomography will be presented.

You are invited to contribute to this Special Issue by sending your articles to be considered for publication.

Prof. Dr. DIDO YOVA
Guest Editor

Manuscript Submission Information

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Keywords

  • 3D and multidimensional microscopy
  • single molecule spectroscopy
  • biophotonic innovative systems
  • optical biopsy
  • optical coherence tomography

Published Papers (1 paper)

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Research

12 pages, 12195 KiB  
Article
Metabolic Profiling of Type 2 Diabetes Patients after Bariatric Surgery by Raman Spectroscopy
by Arianna Bonizzi, Marta Sevieri, Leopoldo Sitia, Andrea Rizzi, Lorenzo Conti, Fabio Corsi, Carlo Morasso and Serena Mazzucchelli
Appl. Sci. 2021, 11(22), 10710; https://0-doi-org.brum.beds.ac.uk/10.3390/app112210710 - 12 Nov 2021
Viewed by 1679
Abstract
Background: Bariatric surgery (BS) is an important procedure used for the treatment of morbid obesity and has been proven to improve, or even cure, type 2 diabetes mellitus (T2DM). However, of the patients with T2DM who initially go into remission, a proportion experience [...] Read more.
Background: Bariatric surgery (BS) is an important procedure used for the treatment of morbid obesity and has been proven to improve, or even cure, type 2 diabetes mellitus (T2DM). However, of the patients with T2DM who initially go into remission, a proportion experience a relapse during the follow-up. In this context, Raman spectroscopy (RS) could be a promising technique for monitoring the metabolic profile of patients after surgical treatment with the aim of improving their postsurgical management. Methods: Fourteen obese patients with T2DM were recruited. Clinical parameters, adipokines, ghrelin, Fibroblast growth factor 19 (FGF-19) values, and Raman spectra were collected and analyzed before and after surgery. RS results were compared with profiles obtained from 23 healthy subjects (HC), to observe whether the metabolic fingerprint of bariatric patients normalized during the surgical follow-up. Results: The reduction in anthropometric measures and improved glycemic control and lipid profile after surgical treatment highlighted the benefits of BS. Consequently, adipokines, ghrelin and FGF-19 concentration returned to normal values after surgery. However, RS data highlighted an altered metabolic profile even after BS. Conclusion: RS suggests that BS does not fully restore the metabolic profile of patients in the immediate follow-up after the surgery. Full article
(This article belongs to the Special Issue Applications of Biophotonics in Biology and Medicine)
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