Special Issue "Bioinformatics Applications of MicroRNAs in Cancer Research"

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Computing and Artificial Intelligence".

Deadline for manuscript submissions: closed (30 November 2021).

Special Issue Editors

Prof. Dr. Giuseppe Sammarco
E-Mail Website
Guest Editor
Department of Health Sciences, University of Catanzaro, Viale Europa, 88100 Catanzaro CZ, Italy
Interests: general and colorectal surgery
Dr. Giulio Ferrero
E-Mail Website
Guest Editor
Dipartiment of Computer Science, Università degli Studi di Torino, 10149 Torino, Italy
Interests: computational biology; systems biology; functional genomics
Special Issues, Collections and Topics in MDPI journals
Dr. Gaetano Gallo
E-Mail Website
Guest Editor
Department of Medical and Surgical Sciences, University of Catanzaro, Viale Europa, 88100 Catanzaro CZ, Italy
Interests: abdominal surgery; colorectal cancer; colorectal surgery; digestive surgery; miRNA; MMP (Matrix metalloproteinase); proctology; surgery; translational research
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In the last few years, the field of epigenetics has significantly expanded due to the discovery of new high-throughput microarray-based miRNA profiling platforms such as next-generation sequencing (NGS) that allow genome-wide microRNA (miRNA) and mRNA expression analyses.

miRNAs are a class of short endogenous single-stranded non-coding RNAs that are 18–25 nucleotides in length and are able to post-transcriptionally repress gene expression by binding to the 3’untranslated region (UTR) of their target mRNAs.

They were first discovered in 1993 as a developmental regulator of the nematode Caenorhabditis elegans. Since then, miRNAs have been found in different body fluids, such as serum, plasma, urine, saliva and tissues, and several studies have reported their roles in a variety of biological processes and immune responses, including angiogenesis, drug resistance and tumorigenesis.

Computational biology has improved our understanding and characterization of miRNAs. Bioinformatics and Systems Biology approaches have provided tools and pipelines to facilitate the discovery of novel miRNA loci and isoforms, as well as the characterization of miRNAs regulated genes and signaling pathways.

The aim of this Special Issue is to provide a series of state-of-the-art manuscripts, including both original contributions and review articles, in order to reach a complete understanding of the role of Bioinformatics Applications of MicroRNAs in Cancer Research.

Prof. Dr. Giuseppe Sammarco
Dr. Giulio Ferrero
Dr. Gaetano Gallo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microRNAs
  • small RNAs
  • cancer
  • gastrointestinal cancers
  • urologic cancers
  • gynecological cancers
  • bioinformatics
  • microbiome

Published Papers

There is no accepted submissions to this special issue at this moment.
Back to TopTop