Biomicrofluidic Systems for Diagnostics and Clinical Applications

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: closed (10 June 2022) | Viewed by 3700

Special Issue Editor


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Guest Editor
Assistant Professor of Biomedical Engineering, Rangos School of Health Sciences, Department of Engineering, Duquesne University, Pittsburgh, PA 15282, USA
Interests: microfluidics; bioMEMS/NEMS; in vitro diagnostics; lab-on-a-chip; medical devices; optical biosensors; super-resolution imaging; soft lithography; micropatterning

Special Issue Information

Dear Colleagues,

We are inviting submissions to this Special Issue on “Biomicrofluidic Systems for Diagnostics and Clinical Applications”.

Biomicrofluidics is a burgeoning field of research with a growing number of academic research groups, a plethora of startup companies developing niche products, and an ever-expanding market share in the biomedical industry. Recent trends in diagnostics and clinical care call for novel micro and nanoscale technologies addressing unmet needs in human health. For instance, personalized medicine entails a spectrum of new approaches which facilitate point-of-care diagnostics and wearable sensor technologies. Biomicrofluidic systems will play a vital role in addressing some of these challenges and help to shift the paradigm in many biomedical and clinical applications.

In this Special Issue, we invite submissions exploring cutting-edge research and recent advances on biomicrofluidic systems for diagnostics and clinical applications. We welcome submissions for original research articles and review articles on topics including but not limited to in vitro diagnostics, point-of-care testing, cell trapping, manipulation and separation methods, microfluidic biosensors based on optical, electrical, acoustical and magnetic transduction mechanisms, and organ-on-chips. Applications include well-established ones, such as infectious disease diagnostics, blood chemistry, monitoring of cardiac and cancer markers, cell sorting, and fertility, as well as emerging ones, such as drug development and testing, immunoengineering, and cryopreservation.

Dr. Melikhan Tanyeri
Guest Editor

Manuscript Submission Information

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Keywords

  • Biomicrofluidics
  • Lab-on-a-chip
  • Organ-on-a-chip
  • In vitro diagnostics
  • Point-of-care testing
  • bioMEMS
  • Paper microfluidics
  • Cell trapping, sorting
  • Drug delivery
  • Tissue engineering
  • Omics analysis
  • Drug discovery/development

Published Papers (1 paper)

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Research

17 pages, 3622 KiB  
Article
Control System Applied to the Microinjection of Artificial Tears for Severe Dry Eye Treatment
by Narcisse Meni-Babakidi, Gonzalo Viramontes-Gamboa, Laura Alicia Ibarra-Bracamontes and Israel Luna-Reyes
Appl. Sci. 2020, 10(5), 1883; https://0-doi-org.brum.beds.ac.uk/10.3390/app10051883 - 10 Mar 2020
Cited by 3 | Viewed by 2973
Abstract
This paper presents a portable automated teardrop microinjection system as a practical solution for patients suffering from severe dry eye. The electronic device for the controlled and continuous injection of artificial tears is designed, assembled, and tested for performance and stability. It is [...] Read more.
This paper presents a portable automated teardrop microinjection system as a practical solution for patients suffering from severe dry eye. The electronic device for the controlled and continuous injection of artificial tears is designed, assembled, and tested for performance and stability. It is controlled via Wi-Fi from an Android programmable device. Its design is based on the physicochemical properties of artificial tears, and with both production costs and portability in mind. The system was modeled according to the V methodology of the association for professional German engineers VDI 2206 standard. The microinjector handles a wide range of internal variables such as tears flow rate (0.13 to 60 μL/min), tears viscosity (up to 600 Pa·s), temperature (up to 60 °C), injected volume of tears, and time between consecutive injections. For evaluation purposes, a comprehensive set of experimental tests were carried out to the system, comparing the actually delivered amount of tears, flow rate, and prescribed time vs. programmed values, the error was ∼0.2% for commercially available artificial tears. Full article
(This article belongs to the Special Issue Biomicrofluidic Systems for Diagnostics and Clinical Applications)
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