Modelling, Analysis, Simulation, Control, and Optimization of Bioprocesses in Bioreactors II
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".
Deadline for manuscript submissions: closed (15 December 2021) | Viewed by 3155
Special Issue Editor
Interests: reaction and bioreaction engineering
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bioprocess engineering deals with the design and development of equipment and processes for the manufacturing of wide range of products from biological materials. Treatment of waste water is also included in this field. Bioprocess engineering connects mathematics, biology and industrial design, and consists of various spectrums like designing of bioreactors, study of fermentors. It also deals with studying various biotechnological processes used in industries for large scale production of biological products. Bioprocess engineering include the work of mechanical, electrical, and industrial engineers to apply principles of their disciplines to processes based on using living cells or sub-components of such cells. It is becoming an engineering and science discipline with extreme importance and enormous potential.
The most crucial industrial production units in biotechnology are bioreactors. Although the basic operating principle of bioreactors is elementary, a great deal of knowledge of bioreactors is required to ensure the quality, quantity, and economy of the products. In the last decades, we have witnessed intensive research and development, considering the bioreactors of various forms. Investigations in the field of mathematical modelling and control are incredibly important. Dynamic modelling of bioreactors is a challenging problem due to the complexity of cellular metabolisms. The main control objective is to maximize the total production of the desired product. The appropriate strategy for achieving the control objective depends on the bioreactor geometry, bioprocess source media, bioreactor operating mode, the availability of the online measurements, the selected control algorithm, and the accuracy of the dynamic bioreactor model.
It is, therefore, crucial that all employed in the field of bioprocess engineering have enough state-of-the-art knowledge and that they have access to the experiences gained by other engineers and scientists. These are the primary aims of this special issue: Engineers and academics who have discoveries transfer them to others.
The area of the special issue is vast. We expect contributions from the fields of:
- bioreactor geometry design,
- sensors and actuators for bioreactors,
- theoretical and experimental (identification) modeling of bioprocesses in bioreactors,
- monitoring and data processing for physical and chemical quantities in bioreactors,
- bioreactor control systems with advanced control concepts
- new structures and algorithms,
- optimization of bioreactors.
Prof. Dr. Andreja Gorsek
Guest Editor
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Keywords
- biotechnology
- bioprocess engineering
- bioreactors
- modeling
- analysis
- simulation
- control
- sensors
- actuators
- optimization
