Electrical Control of Cell Behavior: Potential Mechanisms and Therapies
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".
Deadline for manuscript submissions: closed (31 July 2021) | Viewed by 281
Special Issue Editor
Special Issue Information
Dear Colleagues,
Electricity is an inherent property of every cell, whether bacterial, plant or animal. The notion that cells and tissues generate electric fields naturally, within and around themselves, by ion transport across membranes and epithelia, is often underappreciated. Recent advances in techniques to detect, interpret, and manipulate the electrical signals in cellular environments have improved understanding of how cells interact with electric fields. However, several important questions remain: Mechanistically, in the absence of ‘electro-receptors’ akin to the ligand-specific receptors key to chemotropism, how do cells read the electrical gradient and translate it into an appropriate intracellular response? What is the spatiotemporal electrical geography in intact tissues? How does it change upon injury? How do we optimize electrical stimulation protocols to facilitate tissue repair after injury?
This Special Issue addresses these topics by exploring the techniques used to expose cells and tissues to electric fields and considers how to assess cell responses and how this knowledge can be used to improve tissue repair and regeneration.
Topics for this Special Issue may include but are not restricted to:
- In vitro systems for applying electric fields to cells and tissues;
- Techniques for quantifying and modeling dynamic cell responses to electric fields;
- Techniques for measuring and mapping electric fields within cells and tissues;
- Electrode materials for electrostimulation;
- The cellular mechanisms underpinning innovative electrotherapies.
Dr. Ann Rajnicek
Guest Editor
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- bioelectricity
- electric field
- electrodes
- regeneration
- galvanotaxis
- ion transport
- membrane potential
- transepithelial potential
- cell migration
- regeneration
