Dear Colleagues,

Raman spectroscopy (RS) has already been proven to be a formidable tool for the study of complex biological processes, detection of specific endogenous biomarkers, assessment of pathological conditions, and disease-site tracking with exogenous contrast agents for diagnostic purposes. RS research has encouraged cross-disciplinary interaction between researchers from different fields,  including physicists, engineers, chemists, biochemists, biologists, biostatisticians, and medical doctors, leading to the development of several Raman-based methods and technologies covering numerous applications in the biomedical field. The field is now also benefitting from the use of the new analytical methods provided by artificial intelligence. These new approaches allow the rapid and accurate analysis of the large volume of data typically generated during the study of biological samples by vibrational spectroscopy.

This Special Issue aims to collect research papers and review articles focused on the evolution of Raman spectroscopy with the aim of answering technological and analytical needs in the biological and medical fields.

To sustain and stimulate the involvement of young and emerging researchers (less than 40 years old at the time of submission), we strongly encourage their participation in a prominent role (first author and/or corresponding author, shared or not with a senior author).

The Special Issue topics include, but are not limited to:

• Tools and technologies: spontaneous RS, Raman imaging, stimulated RS (e.g., SRS and CARS), nano-enhanced RS (e.g., SERS), deep RS (e.g., SORS and SESORS), RS probes designed or applied to biological/biomedical applications;
• Applications from biochemical studies to in vivo studies, from cells and tissues to biofluids; and
• Biostatistical and chemometric tools

You may choose our Joint Special Issue in Optics.

Dr. Renzo Vanna
Dr. Carlo Morasso
Dr. Priyanka Dey
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• Raman spectroscopy
• Raman Imaging
• clinical spectroscopy
• CRS
• SERS
• SORS
• SESORS
• artificial intelligence
• vibrational spectroscopy
• diagnosis
• nanotechnology