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Applied Sciences
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Advances in Gut Microbiome and Human Health
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Advances in Gut Microbiome and Human Health

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: closed (15 June 2022) | Viewed by 2376

Special Issue Editor

Dr. Thomas T. Y. Wang

E-Mail Website
Guest Editor
Diet, Genomics and Immunology Laboratory, Beltsville Human Nutrition Research Center, USDA-ARS, Beltsville, MD 20705, USA
Interests: diet; cancer prevention
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The gut microbiome has emerged as one of the critical modulatory factors of human health. However, the field is still young, and several challenges are prevalent. This Special Issue seeks to invite manuscripts that address the shortcomings that persist in this research area. This Special Issue will focus on human health using human subjects, in-vivo models and will consider manuscripts related to the following areas: (1) technological improvement of analysis of the gut microbiome, including bioinformatics tools; (2) mechanistic studies addressing the biological effects that result from changes in the gut microbiome; (3) studies elucidating the impact of gut microbiome on etiology, progression and prevention of diseases. Additionally, manuscripts that center on the causal effects of gut microbiome changes on human health are highly desirable. 

Dr. Thomas T. Y. Wang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gut microbiome
  • diet
  • diseases
  • human health
  • mechanism
  • metagenomic analysis

Published Papers (1 paper)

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Research

8 pages, 784 KiB  
Communication
Short Communication: Obesity Intervention Resulting in Significant Changes in the Human Gut Viral Composition
by Diego Sandoval-Vargas, Nataly D. Concha-Rubio, Paola Navarrete, Matías Castro and Daniel A. Medina
Appl. Sci. 2021, 11(21), 10039; https://0-doi-org.brum.beds.ac.uk/10.3390/app112110039 - 27 Oct 2021
Cited by 4 | Viewed by 1951
Abstract
Obesity is a health problem of global concern that negatively impacts quality of life. Various studies have implicated obesity in the disruption of the normal microbiome composition. The virome consists of a collection of all the viruses that inhabit a particular niche. However, [...] Read more.
Obesity is a health problem of global concern that negatively impacts quality of life. Various studies have implicated obesity in the disruption of the normal microbiome composition. The virome consists of a collection of all the viruses that inhabit a particular niche. However, the study of such viruses that compose the human gut microbiome in the context of obesity has been paid little attention. One interesting aspect of virome study is the description of phages that can specifically interact with the bacterial component of the microbiota and modulate the microbiome’s dynamics. Previous work showed that the microbiota composition changes after obesity treatment and that these changes are country specific. In this work, we perform a quick gut viral composition of the gut microbiota of patients from Denmark, Italy, and Chile before and after obesity intervention using metagenomic sequences previously published and bioinformatics tools. Our results showed that obesity treatment results in significant changes in the human gut viral composition. These results conclude that the virome composition changes after obesity intervention by suggesting that changes can be related to the microbiota rearrangements reported in other works and may be involved in microbial dynamics after treatment. Full article
(This article belongs to the Special Issue Advances in Gut Microbiome and Human Health)
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