Selected Papers from the 2016 International Conference on Nanoscience and Nanotechnology

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Nanotechnology and Applied Nanosciences".

Deadline for manuscript submissions: closed (21 December 2016) | Viewed by 7264

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1. Department of Electrical and Information Engineering, University of Cassino and Southern Lazio, 03043 Cassino, Italy
2. National Institute for Nuclear Physics (INFN), 00186 Roma, Italy
Interests: electromagnetic modeling
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Dear Colleagues,

The 2016 International Conference on Nanoscience and Nanotechnology (N&N) was held in Frascati (Italy) from 26 to 29 September 2016. Since 2000, the conference has been an international meeting in the area of nanotechnology devoted to recent developments in nanoscience and its manifold technological applications. The conference contributions come from frontier nanoscience research developments and innovative nanotechnologies in the areas of biology, medicine, aerospace, optoelectronics, energy, materials and characterizations, low-dimensional nanostructures and devices.

Prof. Dr. Antonio Maffucci
Guest Editor

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Published Papers (1 paper)

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Article
Use of Ferritin-Based Metal-Encapsulated Nanocarriers as Anticancer Agents
by Luciana Mosca, Elisabetta Falvo, Pierpaolo Ceci, Elena Poser, Ilaria Genovese, Giulia Guarguaglini and Gianni Colotti
Appl. Sci. 2017, 7(1), 101; https://0-doi-org.brum.beds.ac.uk/10.3390/app7010101 - 21 Jan 2017
Cited by 13 | Viewed by 6976
Abstract
The ability of ferritin to bind and deliver metals and metal-based drugs to human neuroblastoma SH-SY5Y cells was studied. We used heavy chain (H) ferritin-based metal-containing nanocarriers to test whether these constructs, which are able to cross the blood-brain barrier, may be used [...] Read more.
The ability of ferritin to bind and deliver metals and metal-based drugs to human neuroblastoma SH-SY5Y cells was studied. We used heavy chain (H) ferritin-based metal-containing nanocarriers to test whether these constructs, which are able to cross the blood-brain barrier, may be used for the delivery of toxic molecules to brain cells, and to study their effect on the viability and cellular redox homeostasis of human neuroblastoma cells. We show that metal-containing nanocarriers are efficiently captured by SH-SY5Y cells. Iron-containing nanocarriers have a proliferative effect, while silver and cisplatin-encapsulated nanocarriers determine concentration-dependent neuroblastoma cell death. This work is a proof of concept for the use of ferritins for the delivery of toxic molecules to brain tumors. Full article
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