Special Issue "Modern Molecular Imaging: New Frontiers in Biotechnology"

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Food Science and Technology".

Deadline for manuscript submissions: closed (10 October 2021).

Special Issue Editors

Prof. Dr. Shu Taira
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Guest Editor
Faculty of Food and Agricultural Sciences, Fukushima University, Kanayagawa, Fukushima 960-1296, Japan
Interests: imaging analysis; nanotechnology; agricultural sciences; nutrition
Prof. Dr. Yuki Sugiura
E-Mail Website
Guest Editor
School of Medicine, Keio University, Tokyo, Japan
Interests: biochemistry; analytical chemistry; mass spectrometry; lipidomics; metabolomics; proteomics
Special Issues and Collections in MDPI journals
Prof. Dr. Ken-ichiro Nakajima
E-Mail Website
Guest Editor
Division of Endocrinology and Metabolism, National Institute for Physiological Sciences, Okazaki-shi, Aichi-ken 444-0864, Japan
Interests: nutrient imaging; food science; neuronal imaging; appetite; in vivo imaging

Special Issue Information

Dear Colleagues, 

The final, scientific goal of this Special Issue is not just to look at a limited view of molecular imaging, but a far wider scope that will bring new knowledge from different disciplines to society.

Currently, we face an unprecedented crisis that threatens human life. For this reason, as scientists, we have to begin serious research to overcome this crisis, using scientific intelligence, knowledge, and technology, all working together to find solutions.

Medical research is important and food science helps promote a healthy body and mind. The fundamental task of food science is the exploration of food function, its health effects, and the relationship between chemical compounds and the body.

This Special Issue covers nutritional science, analytical chemistry, biology, among other disciplines. The word ‘frontier’ in the title has two meanings: it relates to advanced research, but also the researcher and their ambition. In this age, young researchers have great potential, despite often struggling without seeing the light of day. We hope that our concept appeals to a wide range of scientists and researchers and that they will submit an interesting article to this Special Issue.

Prof. Dr. Shu Taira
Prof. Dr. Yuki Sugiura
Prof. Dr. Ken-ichiro Nakajima
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Food science
  • Nutrition
  • Food processing and storage
  • Analytical method
  • Imaging

Published Papers (1 paper)

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Research

Article
Comparative Analysis of Derivatization Reagents for Catecholamines and Amino Acids
Appl. Sci. 2021, 11(13), 6217; https://0-doi-org.brum.beds.ac.uk/10.3390/app11136217 - 05 Jul 2021
Viewed by 453
Abstract
We compared four derivatization reagents to analyze catecholamines and amino acids by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. 2,4,6-Trimethylpyrylium tetrafluoroborate (TMPy), 2,4-diphenyl-pyranylium tetrafluoroborate (DPP-TFB), 4-(anthracen-9-yl)-2-fluoro-1-methylpyridin-1-ium iodide (FMP-10), and triphenyl pyrilium (TPP) were used as derivatization reagents that can specifically modify primary amines or [...] Read more.
We compared four derivatization reagents to analyze catecholamines and amino acids by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. 2,4,6-Trimethylpyrylium tetrafluoroborate (TMPy), 2,4-diphenyl-pyranylium tetrafluoroborate (DPP-TFB), 4-(anthracen-9-yl)-2-fluoro-1-methylpyridin-1-ium iodide (FMP-10), and triphenyl pyrilium (TPP) were used as derivatization reagents that can specifically modify primary amines or hydroxy groups in target molecules. Three derivatization reagents, not including TPP, reacted with all target molecules. The derived catecholamines dopamine and L-DOPA, and the amino acids GABA and glycine, were efficiently ionized in comparison with non-derivatized targets. Comparative analysis indicated that TMPy and FMP-10 produced general increases in signal-to-noise ratios (S/N), whereas DPP and TPP produced specific increases in the S/N of GABA and DA. Notably, TMPy is a small molecule that efficiently reacts with target molecules due to the absence of high bulk and steric hinderance. Full article
(This article belongs to the Special Issue Modern Molecular Imaging: New Frontiers in Biotechnology)
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