Novel Strategies to Improve the Performance of Nanomedicines
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Nanotechnology and Applied Nanosciences".
Deadline for manuscript submissions: closed (31 January 2022) | Viewed by 345
Special Issue Editor
Special Issue Information
Dear Colleagues, Dear Readers,
The application of nanotechnology in medicine is positively impacting healthcare with the introduction of several successful nanoformulations. Recent advancements in this field allowed for the generation of nano-imaging agents for diagnosis and nanomedicines for the treatment of a wide range of diseases. Imaging agent, drugs, therapeutic bio-molecules can be encapsulated inside sub-micrometer vectors of different nature and composition, to improve their efficacy while reducing their toxicity.
Despite the considerable steps forward made in the last 20 years, and the high number of formulations proposed in the open literature, only few product were translated to clinical use. This was in most of the cases linked to a series of limits related to a sub-optimal amount of particles reaching the target or to nanotoxicity. Facing this limits represents an intriguing challenge for researchers, and innovative possibilities are arising in the rational design of:
- Nanoparticles which are more capable to negotiate biological barriers (endothelial barrier, mononuclear phagocytic system, endosomal compartment, et cet.);
- Nanoparticles with an increased targeting ability;
- Strategies to minimize acute and chronic toxicity related to the vectors;
- Co-delivery strategies for therapeutic and theranostic applications.
The present Special Issue will collect original articles and reviews in which authors propose novel strategies for improving nanoparticles performances, not necessarily limited to the four listed. Every innovative refinement, aimed to design more effective nanoformulation, will be considered.
Sincerely,
Dr. Roberto Palomba
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
