Dear Colleagues,

Tissue engineering is a multidisciplinary field integrating chemistry, engineering, biology, and medicine. To achieve successful tissue regeneration, collaborative studies on the synthesis, characterization, and application of many tissue engineering strategies are yet to be completed. Nanomaterials are used in tissue engineering to accomplish the structural and functional restoration of defective body parts by developing constructs that are as similar as possible to the native tissue. Despite the successful advances already made in this field, the development of scaffold that provides a proper extracellular environment for regenerating tissue, including biophysical (topography) and biochemical (delivery of bioactive molecules) cues, is still an unmet need in tissue engineering. Physicochemical interaction between cells and materials represents the major determinant in the success or failure of tissue engineering. Cells interact with the surrounding environment by nanoscale extracellular signals. The purpose of nanoscale tissue engineering is to channel these interactions through nanostructured biomaterials and to guide cellular behaviors towards regeneration.

This Special Issue focuses on three main topics: (i) fabrication of nanomaterials for tissue engineering application; (ii) nanomaterial applications in soft tissue engineering, including cardiac, neural, and cartilage tissue engineering; and (iii) nanomaterial applications in hard tissue engineering, including bone, dental, and craniofacial tissue engineering. Contributions dealing with biopolymers such as polysaccharides and proteins are encouraged.

Dr. Antonio Di Martino
Dr. Kadir Ozaltin
Guest Editors

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• biomaterials
• nanomaterials
• regenerative medicine
• tissue engineering
• biopolymers