Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.5
2.7
Journals
Applied Sciences
Special Issues
Effects of Probiotics on Host Health
share announcement

Effects of Probiotics on Host Health

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Food Science and Technology".

Deadline for manuscript submissions: closed (10 February 2022) | Viewed by 19282

Special Issue Editors

Dr. Linda van de Burgwal

E-Mail Website
Guest Editor
Athena Institute, Vrije Universiteit Amsterdam, 1059 HV Amsterdam, The Netherlands
Interests: probiotics; infectious diseases; one health; public health; public-private partnerships; valorization; innovation
Prof. Dr. Eric Claassen

E-Mail Website
Guest Editor
Athena Institute, Vrije Universiteit Amsterdam, 1059 HV, Amsterdam, The Netherlands
Interests: probiotics; vaccines; industry

Special Issue Information

Dear Colleagues,

It is our pleasure to announce the opening of a new Special Issue in the Applied Science journal.

Through technological advances, it has become increasingly clear that human health and wellbeing are dependent on a healthy microbiome, with the microbiome playing an active role in modulating the host immune system.

The effects of probiotics on the immune system and host health, however, are difficult to disentangle in the heterogeneous study context of the gut microbiome. With the clinical evidence base for probiotics being considered insufficient to support efficacy claims by the EFSA, innovation in this field is in dire need of novel approaches to determine efficacy. A patient-centered approach that prioritizes unmet needs and demands from the patient perspective is called for.

This issue welcomes novel research on outcomes and mechanisms of immunomodulation through probiotics, as well as approaches to study these outcomes and mechanisms in a rigorous fashion. The latter includes large-scale human studies, strategies to gain insight into host phenotypes and environmental lifestyle data, preclinical models, and novel patient-centered study approaches, like n=1 approaches.

Dr. Linda van de Burgwal
Prof. Dr. Eric Claassen
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • immunomodulation
  • microbiota
  • probiotics
  • research models
  • host health

Published Papers (4 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Review

14 pages, 1449 KiB  
Article
Effect of Lactobacillus paracasei HII01 Supplementation on Total Cholesterol, and on the Parameters of Lipid and Carbohydrate Metabolism, Oxidative Stress, Inflammation and Digestion in Thai Hypercholesterolemic Subjects
by Chaiyavat Chaiyasut, Yaowalak Tirawat, Bhagavathi Sundaram Sivamaruthi, Periyanaina Kesika, Subramanian Thangaleela, Suchanat Khongtan, Nanticha Khampithum, Sartjin Peerajan, Khontaros Chaiyasut, Sasithorn Sirilun and Phakkharawat Sittiprapaporn
Appl. Sci. 2021, 11(10), 4333; https://0-doi-org.brum.beds.ac.uk/10.3390/app11104333 - 11 May 2021
Cited by 10 | Viewed by 2042
Abstract
Hypercholesterolemia is one of the leading causes of cardiovascular disease. Probiotics can help to improve high blood lipid levels in hypercholesterolemia patients. Lactobacillus paracasei has been reported to have beneficial effects in several subjects; however, there is a lack of studies on Thai [...] Read more.
Hypercholesterolemia is one of the leading causes of cardiovascular disease. Probiotics can help to improve high blood lipid levels in hypercholesterolemia patients. Lactobacillus paracasei has been reported to have beneficial effects in several subjects; however, there is a lack of studies on Thai hypercholesterolemic subjects. Thus, this study was conducted in order to investigate the effect of L. paracasei HII01 on cholesterol, oxidative stress, and other biomarkers. Fifty-two subjects were randomized into two groups: the L. paracasei treatment group and the placebo group. The study was conducted over an intervention period of 12 weeks of supplementation. The results show that L. paracasei HII01 significantly reduced the total cholesterol (TCH), triglycerides (TGs), tumor necrosis factor (TNF)-α and lipopolysaccharide (LPS) of the patients, and increased their HDL, total antioxidant capacity (TAC) and propionic acid compared to the placebo group. Moreover, the supplementation of L. paracasei HII01 significantly increased lactic acid, IL-10 and IFN-γ, and substantially decreased malondialdehyde (MDA) at the end of the treatment. The results suggest that L. paracasei HII01 improves the blood lipid profile, reduces oxidative stress, and is beneficial for health among Thai hypercholesterolemic subjects. Full article
(This article belongs to the Special Issue Effects of Probiotics on Host Health)
►▼ Show Figures

Figure 1

Review

Jump to: Research

18 pages, 537 KiB  
Review
Influence of Probiotic Supplementation on Health Status of the Dogs: A Review
by Bhagavathi Sundaram Sivamaruthi, Periyanaina Kesika and Chaiyavat Chaiyasut
Appl. Sci. 2021, 11(23), 11384; https://0-doi-org.brum.beds.ac.uk/10.3390/app112311384 - 01 Dec 2021
Cited by 8 | Viewed by 9023
Abstract
Most commonly, pet dogs suffer from gastrointestinal (GI) diseases due to careless eating behaviors, such as eating food other than dog food; excess or insufficient nutrient intake of food leading to malnutrition, which could be harmful to dogs; a lack of digestive enzymes; [...] Read more.
Most commonly, pet dogs suffer from gastrointestinal (GI) diseases due to careless eating behaviors, such as eating food other than dog food; excess or insufficient nutrient intake of food leading to malnutrition, which could be harmful to dogs; a lack of digestive enzymes; food intolerance or allergies; infections; and/or breed-related hypersensitivities. Probiotics are live microorganisms that deliver health benefits to the host when administrated in an adequate amount. The possible mechanism behind probiotics’ beneficial effects could be their positive regulation of the host’s intestinal microbiota. Probiotics are reported to have therapeutic properties against canine GI and other diseases. The most suitable dosages and applications of probiotics have not been evaluated extensively. The present review summarizes current knowledge regarding the benefits of probiotics and the changes in canine microbiota during probiotic interventions. This literature review provides clinical evidence for probiotics’ beneficial effects in preventing or treating canine ill-health conditions. Based on current knowledge, subsequent researchers could develop or improve probiotics-based canine pharmacological products. Full article
(This article belongs to the Special Issue Effects of Probiotics on Host Health)
►▼ Show Figures

Figure 1

16 pages, 320 KiB  
Review
The Antiviral Potential of Probiotics—A Review on Scientific Outcomes
by Periyanaina Kesika, Bhagavathi Sundaram Sivamaruthi, Subramanian Thangaleela and Chaiyavat Chaiyasut
Appl. Sci. 2021, 11(18), 8687; https://0-doi-org.brum.beds.ac.uk/10.3390/app11188687 - 17 Sep 2021
Cited by 9 | Viewed by 3878
Abstract
A rich repertoire of research studies on probiotics has been documented as one of the therapeutic agents or adjuvants for vaccines in treating viral infections. It is well known that the immunomodulatory properties of probiotics reduce the severity of viral infections. The efficacy [...] Read more.
A rich repertoire of research studies on probiotics has been documented as one of the therapeutic agents or adjuvants for vaccines in treating viral infections. It is well known that the immunomodulatory properties of probiotics reduce the severity of viral infections. The efficacy of probiotics alone and combined boost up the host’s innate immunity, thereby developing a robust antiviral paradigm. As dietary and therapeutic measures, probiotics potentially work as an alternative for those who lack access to vaccines or antiviral drugs. Potential probiotic mechanisms include competing with pathogens for nutrients and colonization sites, producing antimicrobial metabolites and enhancing protective immune responses. The live probiotics can reach and colonize the host animals’ intestines then confer the health benefits by improving the host’s natural defence against viral infections. The research studies on probiotics suggest that they reduce the risk of viral infections, yet the innermost mechanisms are still unknown. The reason for scripting this review is to discuss the current developments in probiotic therapeutic measures and their probable insights into antiviral agents. Full article
(This article belongs to the Special Issue Effects of Probiotics on Host Health)
12 pages, 1384 KiB  
Review
The Administration of Probiotics against Hypercholesterolemia: A Systematic Review
by Bhagavathi Sundaram Sivamaruthi, Muruganantham Bharathi, Periyanaina Kesika, Natarajan Suganthy and Chaiyavat Chaiyasut
Appl. Sci. 2021, 11(15), 6913; https://0-doi-org.brum.beds.ac.uk/10.3390/app11156913 - 27 Jul 2021
Cited by 8 | Viewed by 3660
Abstract
Hypercholesterolemia is a key factor in the progression of atherosclerosis and cardiovascular disease (CVD). CVD is a significant public health concern with a high death rate. Some of the main factors linked to CVD include genetics and lifestyle. Dyslipidemia has been one of [...] Read more.
Hypercholesterolemia is a key factor in the progression of atherosclerosis and cardiovascular disease (CVD). CVD is a significant public health concern with a high death rate. Some of the main factors linked to CVD include genetics and lifestyle. Dyslipidemia has been one of the factors related to the onset of several CVD-related diseases. Several clinicopathological studies have shown a correlation between high cholesterol levels, particularly low-density lipoprotein cholesterol (LDL-c), and CVD development. Probiotics have received a lot of attention for various beneficial effects, especially their ability to reduce blood cholesterol in humans. Probiotics were shown in several investigations to affect hypercholesterolemia by influencing cholesterol biosynthesis. The current review focuses on the human dietary interventions with probiotics and their effects on CVD risk factors and hypercholesterolemia. The outcomes are debatable and consider various parameters such as probiotic strain, dosing frequency, therapeutic response, dietary changes, and so forth. As a result, probiotics have the propensity to become dietary supplements in moderate/severe hypercholesterolemic patients, which significantly reduces the CVD risk. Full article
(This article belongs to the Special Issue Effects of Probiotics on Host Health)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-4
Back to TopTop