Special Issue "Advances in Microseparation Technology"
A special issue of Bioengineering (ISSN 2306-5354).
Deadline for manuscript submissions: closed (30 September 2018).
Interests: sustainable manufacturing technologies for biologics and botanicals; key enabling technologies to industrialize innovative manufacturing technologies under QbD-demands; upstream and downstream process integration; model-based process design; quality by design (QbD); continuous bioprocessing (CBP); big data; hybrid models
Special Issues, Collections and Topics in MDPI journals
Special Issue in Processes: Towards Autonomous Operation of Biologics and Botanicals
Needs in novel white and red biotechnology process applications, which are derived from large social needs related to, e.g., the bio-based world and innovative medicine initiatives, are causing new challenging separation tasks of high volume/low cost, as well as low volume/high value products at a reduced cost-of-goods. Therefore, improvements in efficient downstream processing technologies for biotechnology process development and manufacturing are still key-issues under research and development. Process intensification focuses on process integration using consistent design methods for hybrid separations and optimal total process integration methods, based on process modeling, as well as process enhancement activities, such as micro-/milli-structured devices, ultra-sound, microwave, pulsed-electric-field enhances mass transfer and/or novel separation media, e.g., nano-scaled and/or selectivity/capacity enhanced.
Recently, micro-/milli-structured devices have been invented and characterized for different process applications, such as chromatography, membranes, precipitation/crystallization, as well as liquid–liquid extraction and distillation. Novel media have been introduced and mass transfer enhancing energy input described.
Nevertheless, further activities are needed to make design methods, materials and devices more applicable for the community in order to speed up industrialization. Especially in regulated industries, any change in process development and manufacturing technology has to be convincing for regulatory authorities and, therefore, applicants based on sound scientific methods related to consistent transparent data-driven decisions.
This Special Issue will help to bridge the gap between fundamental academia research and industrial utilization. Therefore, any contributions related to the above-mentioned topics and applications are welcome.
Prof. Dr. Jochen Strube
The first round submission deadline: 30 September 2017
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Process Intensification
- Micro Technology
- Downstream Processing