Special Issue "Microbiota and Immune System Crosstalk 2020"
Deadline for manuscript submissions: closed (30 June 2021).
Interests: genetics; biological evolution; experimental and genome evolution; philosophy of biology; study of the human and animal microbiome under an evolutionary and system biology perspective
Interests: pathology; treatment; infection; stem cells; gastroenterology; stem cell isolation; periodontics; PCR; odontoblasts
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Almost a century has passed since Paul de Kruif, in 1926, published his "Microbe Hunter" in which he narrated the first heroes of microbiology. This narrative reflected our idea of a relationship with the microbial world, similar to a war and quite different from the relationship of beneficial mutualism that scientific studies have been demonstrating in recent years. This vision continued unchanged until the early years of this century, considering only some bacteria of our organism as useful to facilitate some intestinal functions and little else. Today, we know that the commensal microorganisms that make up the microbiota resident in the various body districts, in fact, not only support the functions of the human organism, such as metabolism and defense against the proliferation of pathogens, but have a key role in the development of the immune system in the early childhood and, consequently, on the state of inflammation of the body. Early intestinal colonization is important for the development and maintenance of immune tolerance, which in turn is necessary for the prevention of immune-mediated diseases. The lack of development of immunological tolerance in the first months of life, as well as the loss of immunological tolerance in later times, predispose to the appearance of allergic or autoimmune diseases. The purpose of this Special Issue is a collection of scientific contributions for understanding the role of the microbiota and the microbiome in the regulation of the immune system, as well as its possible manipulation by diet and probiotics. Original articles and extensive reviews are preferable, but any type of article, including those on the history of microbiology and the immune system, is welcome.
Prof. Dr. Andrés Moya
Dr. Luigi Santacroce
Prof. Paolo Maggi
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- immune system
- immune tolerance
- autoimmune diseases
- history of immunology
- history of microbiology