Dear Colleagues,

Vascular diseases are among the leading causes of morbidity and mortality worldwide, with manifestations ranging from atherosclerosis and aberrant angiogenesis to devastating bleeding and occlusive thrombosis. Platelets are increasingly becoming recognized as essential participants in these pathologies beyond their function as effectors of thrombotic complications, also linking inflammatory and/or infectious disease with vascular complications. With their ability to regulate angiogenesis and tissue homeostasis and their capacity to sense and modulate the inflammatory processes underlying endothelial dysfunction, the contributions of these small, seemingly inconspicuous cells are manifold.

For this Special Issue, we invite authors to submit research articles and reviews focusing on the cellular and molecular mechanisms involved in vascular diseases, highlighting recent findings on the contribution of platelets as regulators and drivers of vascular diseases, their interplay with vascular and immune cells, and/or their potential to act as targets for diagnostic, preventive, and interventive treatment. We welcome clinical studies as well as studies involving cell culture techniques and mouse models with the aim of expanding current knowledge on the versatile roles of platelets in the complex variety of vascular diseases.

We ask authors to submit an abstract prior to article submission to make sure that their work falls within the scope of this Special Issue.

Sincerely, 

Dr. Waltraud C. Schrottmaier
Dr. Marion Mussbacher
Guest Editors

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• vascular inflammation
• vascular disease
• platelets
• anti-platelet therapy
• endothelial dysfunction
• angiogenesis
• infection
• thrombosis
• atherosclerosis
• platelet–leukocyte aggregates