Dear Colleagues,

Efforts to understand human lung physiology have led to much rewarding progress in the last century. The identification of the relevant mechanisms underlying several lung pathologies has been a vital part of this progress. In this context, we have witnessed that the quality assurance mechanisms of a cell play vital roles in maintaining a strict balance between cell survival and cell death, as well as to systematically respond to external and internal stress, thereby deciding the pathological consequences of various lung diseases. Such quality control already begins at the level of cellular organelles, namely, the endoplasmic reticulum (ER), mitochondria, the proteasome or the lysosome, but all these mechanisms converge into two major cellular surveillance systems: the ubiquitin–proteasome system (UPS) and the autophagy–lysosome pathway.

Considerable efforts are being directed towards understanding how therapeutic interventions can be planned to target such quality control mechanisms in chronic lung diseases. We appreciate such studies in cellular, pre-clinical or clinical models of chronic lung diseases and encourage investigators to submit original research articles as well as review articles focusing on:

1. Identification of genes or gene products involved in cellular quality control mechanisms that could be exploited for novel therapeutic interventions;

2. Identification of novel pharmacological/small molecules that target one or more of the quality control pathways.

Dr. Poornima Mahavadi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.