Nanomechanical Biosensors in Diagnostics, Food, and Environmental Monitoring

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".

Deadline for manuscript submissions: closed (20 May 2022) | Viewed by 3317

Special Issue Editors


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Guest Editor
Department of Mechanical Engineering, National Taipei University of Technology (NTUT), Taipei City 10608, Taiwan
Interests: CMOS BioMEMS based biosensors; nanohybrid paper-based electrochemical biosensors; microfluidics; nanomechanical biosensors

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Guest Editor
Department of Science and Technology (ITN), Campus Norrköping, Linköping University, SE 60174 Norrköping, Sweden
Interests: materials; synthesis; characterization; material application for energy harvesting; devices for sensing; optical and electrical devices
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Guest Editor
Department of Electrical & Computer Engineering, Texas A&M University, TX 77843, USA
Interests: physical informatics; unconditional security; nanomaterials/structures; aging/degradation; percolation; fluctuation-enhanced sensing; noise-based computation; thermal demons/engines; noise: origin, fundamental limits, applications, mitigation; stochastic resonance
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nanomechanical biosensors have been investigated and developed for over two decades—not only because they are promising tools for directly detecting biomolecular interactions with great accuracy, but the detection principles, fabrication techniques, sensing materials, and readout system for developing nanomechanical biosensors are attractive topics for researchers. The microcantilever-based biosensor is a good example of the combination of nanotechnology and biotechnology. High-throughput platforms using arrays of microcantilevers also achieve the simultaneous measurement and read-out of multiple samples. As a result, many engrossing applications have been performed and several platforms are being commercialized. This Special Issue covers the discussion of sensor working principles, the types of sensor format, the fabrication methods, and any applications in chemical and biological analysis, as well as considerations for commercial purpose. Here, we would like to invite talented researchers to join us in this interesting field of study, which has the potential to improve the general welfare of society.

Prof. Dr. Yi-Kuang Yen
Prof. Dr. Magnus Willander
Prof. Dr. Laszlo B. Kish

Guest Editors

Manuscript Submission Information

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Keywords

  • CMOS MEMS
  • Nanomechanics
  • Microcantilever
  • BioMEMS
  • Disposable sensors 
  • Portable sensing platform 
  • Environmental monitoring 
  • Food analysis 
  • Point-of-care testing 
  • Sensing chip array
  • Medical diagnosis
  • Sensing materials
  • Signal enhancement 
  • Gas sensing 
  • Readout system

Published Papers (1 paper)

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Research

11 pages, 4984 KiB  
Article
Development of Er3+, Yb3+ Co-Doped Y2O3 NPs According to Yb3+ Concentration by LP–PLA Method: Potential Further Biosensor
by Cheol-Woo Park and Dong-Jun Park
Biosensors 2021, 11(5), 150; https://0-doi-org.brum.beds.ac.uk/10.3390/bios11050150 - 11 May 2021
Cited by 3 | Viewed by 2218
Abstract
As diagnostic biosensors for analyzing fluids from the human body, the development of inorganic NPs is of increasing concern. For one, nanoceramic phosphors have been studied to meet the increasing requirements for biological, imaging, and diagnostic applications. In this study, Y2O [...] Read more.
As diagnostic biosensors for analyzing fluids from the human body, the development of inorganic NPs is of increasing concern. For one, nanoceramic phosphors have been studied to meet the increasing requirements for biological, imaging, and diagnostic applications. In this study, Y2O3 NPs co-doped with trivalent rare earths (erbium and ytterbium) were obtained using a liquid phase–pulsed laser ablation (LP–PLA) method after getting high density Er, Yb:Y2O3 ceramic targets by Spark plasma sintering (SPS). Most NPs are under 50 nm in diameter and show high crystallinity of cubic Y2O3 structure, containing (222), (440), and (332) planes via HR–TEM. Excitation under a 980 nm laser to a nanoparticle solution showed 525 and 565 nm green, and 660 nm red emissions. The green emission intensity increased and decreased with increasing Yb3+ additive concentration, when the red spectrum continuously strengthened. Utilizing this study’s outcome, we suggest developing technology to mark invisible biomolecules dissolved in a solvent using UC luminescence of Er3+, Yb3+ co-doped Y2O3 NPs by LP–PLA. The LP–PLA method has a potential ability for the fabrication of UC NPs for biosensors with uniform size distribution by laser parameters. Full article
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