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Biosensors
Special Issues
Biosensors Using Quartz Crystal Microbalance
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Biosensors Using Quartz Crystal Microbalance

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: closed (28 February 2021) | Viewed by 2319

Special Issue Editor

Dr. Bartolomeo Della Ventura

E-Mail Website
Guest Editor
Diagnostics of Laboratory and Methodology of Analisys in Sanity, Dipartimento di Fisica "Ettore Pancini", Università degli Studi di Napoli Federico II, 80138 Naples, Italy
Interests: quartz crystal microbalance; biosensing; immunosensors; localized surface plasmon resonance (LSPR); magnetic biosensors; electrochemical biosensors (CV, EIS); nanoparticles functionalization
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recently, immunosensors have attracted attention because of their wide range of applications for the detection of various pathogens. Among the commonly used immunosensors, the quartz crystal microbalances (QCM) have featured prominently as an effective tool for the quantification of the amount of antibodies, antigens, or haptens in complex samples with high sensitivity and specificity.

This Special Issue welcomes both reviews and original research articles in the field of quartz crystal microbalances. There is no limit to the chemical and biological aspects by which an gravimetric immunosensor as QCM can be manufactured.

Dr. Bartolomeo Della Ventura
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Biosensor
  • Quartz crystal microbalance (QCM)
  • Nanoparticle
  • Label-free sensors
  • Localized Surface Plasmon resonance (LSPR)
  • Immuonsensor
  • Gravimetric immunosensor

Published Papers (1 paper)

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Research

11 pages, 2133 KiB  
Article
A Portable, Label-Free, Reproducible Quartz Crystal Microbalance Immunochip for the Detection of Zearalenone in Food Samples
by Shengmiao Liu, Xinyu Liu, Qianwen Pan, Zhihan Dai, Mingfei Pan and Shuo Wang
Biosensors 2021, 11(2), 53; https://0-doi-org.brum.beds.ac.uk/10.3390/bios11020053 - 19 Feb 2021
Cited by 9 | Viewed by 1935
Abstract
This research reports a portable immunochip, based on quartz crystal microbalance (QCM) for label-free, low-cost qualitative detection of zearalenone (ZEN) in food samples. The experimental parameters in the functionalization and working process were evaluated in detail, in order to achieve a high accuracy [...] Read more.
This research reports a portable immunochip, based on quartz crystal microbalance (QCM) for label-free, low-cost qualitative detection of zearalenone (ZEN) in food samples. The experimental parameters in the functionalization and working process were evaluated in detail, in order to achieve a high accuracy and sensitivity. Under optimal conditions, the ZEN concentration at an inhibition ratio of 50% and 15% of the proposed QCM immunochip achieved 3.41 µg L−1 and 0.37 µg L−1, respectively. This portable QCM immunochip also exhibited high specificity, no obvious cross-reaction to five structural analogs of ZEN, and showed other mycotoxins. It could finish the whole qualitative measurement within 30 min, showed good stability during the processes of preparation (SD < 5%, n = 9), storage (frequency response >90%, in PBS at 4 °C for 15 days), and application (frequency response >90% after being reused 6 times). The developed QCM immunochip obtained accurate and repeatable recovery results in ZEN analysis in the chosen food samples (corn, wheat flour, soy sauce, and milk), which had a high correlation (R2 = 0.9844) with that achieved by the HPLC–MS/MS method. In short, this work developed a portable, stable, and reproducible QCM immunochip that could be used for rapid, low-cost, and sensitively measurement of ZEN content in real food samples. Full article
(This article belongs to the Special Issue Biosensors Using Quartz Crystal Microbalance)
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