Special Issue "Enzyme-linked Immunoassay"
A special issue of Biosensors (ISSN 2079-6374).
Deadline for manuscript submissions: closed (30 April 2019).
Interests: analytical chemistry; immunochemical assays; food chemistry
Special Issues and Collections in MDPI journals
Enzyme-Linked ImmunoSorbent Assays (ELISA) have been in use for decades in the medical area and have become increasingly popular as an efficient analytical method for a number of field of application, thanks to their simplicity, speed, low costs, specificity and sensitivity. Nowadays ELISA are largely applied for pharmaceutical, biological, food, forensic and environmental analysis. ELISA relies on the molecular recognition properties of antibodies and on the signal amplification generated by enzymatic probes that also provide versatile detection, by using chromogenic, fluorescent, and chemiluminescent substrates. Although ELISA principles are very well-known, its expanding application to unexplored fields and the requirement for improved sensitivity, rapidity, reliability, and validity are prompting innovation in the domain. Also, advances on artificial receptors (aptamers, molecular imprinted polymers) and novel probes (DNAzyme, inorganic enzyme mimics) are offering ELISA untried opportunities and challenges to further development. The Special issue will cover advances in hapet design, recognition elements, probes, and assay design with emphasis on strategies for improving sensitivity and for expanding application of ELISA to unusual fields of analysis. The special issue also intends to point out benefits of ELISA for improving access to efficient monitoring and for managing large numbers of analysis in the ‘big data’ era.
Prof. Dr. Claudio Baggiani
Prof. Laura Anfossi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Enzyme-linked immunoSorbent Assay
- Broad-specific antibodies
- Artificial antibodies
- Peroxidase mimic
- Hapten design
- High-throughput analysis