Special Issue "Women in Biosensors"

A special issue of Biosensors (ISSN 2079-6374).

Deadline for manuscript submissions: 31 December 2021.

Special Issue Editor

Prof. Dr. Cecilia Cristea
E-Mail Website
Guest Editor
Analytical Chemistry Department, Faculty of Pharmacy, "Iuliu Haţieganu" University of Medicine and Pharmacy 4, Louis Pasteur St., Cluj-Napoca, 400349 Cluj, Romania
Interests: electrochemical and optical sensors; graphene; nanomaterials based electrodes; bioanalysis
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Special Issue Information

Dear Colleagues,

Biosensors received its first Impact Factor (2019) in the recent release of the Journal Citation Reports®. The Impact Factor for Biosensors is 3.240. At the same time, this year, 2020, is Biosensors’ 10th anniversary. Since its launch in 2011, Biosensors has received important support and excellent contributions from women scientists. They have served as our Editorial Board members, Guest Editors, authors, reviewers.

To celebrate and highlight the achievements of women in the biosensors research area, a Special Issue entitled “Women in Biosensors” is being launched, which will present biosensors-related work from leading women scientists. We hope that this Special Issue can further encourage and promote the scientific contributions of women researchers in this field.

This Special Issue welcomes both research and review papers on the most recent and innovative developments of biosensors for applications in the food, health, security, defense, and environmental fields. To be considered for this Special Issue, the corresponding author should be a woman scientist.

Prof. Dr. Cecilia Cristea
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (2 papers)

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Research

Article
Non-Enzymatic Detection of Glucose in Neutral Solution Using PBS-Treated Electrodeposited Copper-Nickel Electrodes
Biosensors 2021, 11(11), 409; https://0-doi-org.brum.beds.ac.uk/10.3390/bios11110409 - 21 Oct 2021
Viewed by 339
Abstract
Transition metals have been explored extensively for non-enzymatic electrochemical detection of glucose. However, to enable glucose oxidation, the majority of reports require highly alkaline electrolytes which can be damaging to the sensors and hazardous to handle. In this work, we developed a non-enzymatic [...] Read more.
Transition metals have been explored extensively for non-enzymatic electrochemical detection of glucose. However, to enable glucose oxidation, the majority of reports require highly alkaline electrolytes which can be damaging to the sensors and hazardous to handle. In this work, we developed a non-enzymatic sensor for detection of glucose in near-neutral solution based on copper-nickel electrodes which are electrochemically modified in phosphate-buffered saline (PBS). Nickel and copper were deposited using chronopotentiometry, followed by a two-step annealing process in air (Step 1: at room temperature and Step 2: at 150 °C) and electrochemical stabilization in PBS. Morphology and chemical composition of the electrodes were characterized using scanning electron microscopy and energy-dispersive X-ray spectroscopy. Cyclic voltammetry was used to measure oxidation reaction of glucose in sodium sulfate (100 mM, pH 6.4). The PBS-Cu-Ni working electrodes enabled detection of glucose with a limit of detection (LOD) of 4.2 nM, a dynamic response from 5 nM to 20 mM, and sensitivity of 5.47 ± 0.45 μA cm2/log10(mole.L1) at an applied potential of 0.2 V. In addition to the ultralow LOD, the sensors are selective toward glucose in the presence of physiologically relevant concentrations of ascorbic acid and uric acid spiked in artificial saliva. The optimized PBS-Cu-Ni electrodes demonstrate better stability after seven days storage in ambient compared to the Cu-Ni electrodes without PBS treatment. Full article
(This article belongs to the Special Issue Women in Biosensors)
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Article
Electrochemical Trimethylamine N-Oxide Biosensor with Enzyme-Based Oxygen-Scavenging Membrane for Long-Term Operation under Ambient Air
Biosensors 2021, 11(4), 98; https://0-doi-org.brum.beds.ac.uk/10.3390/bios11040098 - 27 Mar 2021
Viewed by 1007
Abstract
An amperometric trimethylamine N-oxide (TMAO) biosensor is reported, where TMAO reductase (TorA) and glucose oxidase (GOD) and catalase (Cat) were immobilized on the electrode surface, enabling measurements of mediated enzymatic TMAO reduction at low potential under ambient air conditions. The oxygen anti-interference [...] Read more.
An amperometric trimethylamine N-oxide (TMAO) biosensor is reported, where TMAO reductase (TorA) and glucose oxidase (GOD) and catalase (Cat) were immobilized on the electrode surface, enabling measurements of mediated enzymatic TMAO reduction at low potential under ambient air conditions. The oxygen anti-interference membrane composed of GOD, Cat and polyvinyl alcohol (PVA) hydrogel, together with glucose concentration, was optimized until the O2 reduction current of a Clark-type electrode was completely suppressed for at least 3 h. For the preparation of the TMAO biosensor, Escherichia coli TorA was purified under anaerobic conditions and immobilized on the surface of a carbon electrode and covered by the optimized O2 scavenging membrane. The TMAO sensor operates at a potential of −0.8 V vs. Ag/AgCl (1 M KCl), where the reduction of methylviologen (MV) is recorded. The sensor signal depends linearly on TMAO concentrations between 2 µM and 15 mM, with a sensitivity of 2.75 ± 1.7 µA/mM. The developed biosensor is characterized by a response time of about 33 s and an operational stability over 3 weeks. Furthermore, measurements of TMAO concentration were performed in 10% human serum, where the lowest detectable concentration is of 10 µM TMAO. Full article
(This article belongs to the Special Issue Women in Biosensors)
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